Purpose. This study investigated the anthropometric indices associated with variations in cardiovascular parameters among primary school pupils in Ile-Ife. Method. One thousand and twenty-six pupils (age range 6–14 years, mean age 10.12 years) from ten schools were recruited with parents' informed consent. Anthropometric (Height (Ht), Weight (Wt), Abdominal Circumference (AC)) and cardiovascular (Systolic Blood Pressure (SBP), Diastolic Blood Pressure (DBP), Heart Rate (HR)) parameters were measured using standard instruments and procedures. Blood pressure (BP) was measured after ten minutes of quiet sitting. Body Mass Index (BMI), Rate Pressure Product (RPP) and Pulse Pressure (PP) were estimated. Results. Age, Ht, Wt, BMI, and AC correlated significantly (P < .01) with BP and PP. AC and BMI were predictors of BP, HR, RPP, and PP. Conclusion. Significant correlations exist between age, Ht, Wt, BMI, AC, and BP with weight being a more viable predictor of SBP and age a more viable predictor of DBP.