Anti-aggregation properties of Tris-(2-hydroxyethyl)ammonium salts of aryl(thio)sulfonylacetic acids

Nefedova, T. V.; Кубатиев, Аслан Амирханович; Kazimirovskaya, V. B.; Chernyakhovskaya, B. I.; Мирскова, А. Н.; Guseva, S. A.; Levkovskaya, G. G.; Воронков, М. Г.

doi:10.1007/bf00763269

Cited by 3 publications

(2 citation statements)

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“…Biological activity of hydroxyalkylammonium salts of sulfur-containing acids often exceeds that of the related alkylammonium salts of aroxyacetic acids. Their activity is enhanced with the increase in the oxidation degree of sulfur and depends on the structure of the hydroxyalkylammonium fragment [60,61]. Two salts are the most remarkable: tris(2-hydroxyethyl)ammonium indol-3-yl-and 1-benzylindol-3-ylsulfanylacetate (indacetamin and vilim, respectively).…”

Section: Protatranesmentioning

confidence: 99%

“…Two salts are the most remarkable: tris(2-hydroxyethyl)ammonium indol-3-yl-and 1-benzylindol-3-ylsulfanylacetate (indacetamin and vilim, respectively). Indacetamin exhibits a wide range of biological activity: it is an efficient antiaggregant, stabilizer of cell membrane of erythrocytes and thrombocytes, antioxidant, and protector against ultrasonic and γ-irradiation [62][63][64][65][66][67].…”

Section: Protatranesmentioning

confidence: 99%

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Contribution of the Scientific School of Academician M.G. Voronkov to the Development of the Chemistry of Biologically Active Atranes (Protatranes and Hydrometallatranes) (A Review)

Kondratenko

Кочина

2021

Russ J Gen Chem

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The main results of the many years’ studies of the scientific school of Academician Mikhail G. Voronkov in the field of two subgroups of the atrane family (protatranes and hydrometallatranes) as well as the results of research in continuation of the studies initiated by Academician M. G. Voronkov have been summarized and presented. Long-term studies of atranes under the leadership of M. G. Voronkov have led to the discovery of their unique biological activity and the creation of a series of unique original drugs and means of agricultural chemicalization: biostimulants and adaptogens for agricultural plants, animals, useful insects and microorganisms.

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Section: Protatranesmentioning

confidence: 99%