Anti-anxiety Activity of Cymbopogon citratus (dc.) stapf Leaves Extracts on the Elevated Plus-Maze Model of Anxiety in Mice

Background: Prevalence of psychiatric disorders such as anxiety is a very common and affecting many people all around the world. Currently, many synthetic pharmacological products/ drugs are available in the market to cure the disorder, but associated with various adverse reactions or side effects which may cause discomfort and sometimes other disorders to the patients. In the past years, use of complementary and alternative medicine has increased. The exploration in the areaof herbal psychopharmacology has received much attention as people are using more herbal treatment to benefit their health. Objective: To provide a comprehensive information on anxiety disorder and its herbal treatment Method: In this review, we enlisted the plants, plant extracts and isolated component (if any) along with models used to explore anxiolytic property; in retrospect, still a lot of research required to establish them clinically. Result: Literature revealed that a variety of medicinal plants are effective for the treatment of anxiety likeGinkgo biloba, Passiflora incarnata, Gelsemium sempervirens, Piper methysticum, Bauhinia variegate, Matricaria recutita, Brassica oleracea, Hypericum perforatum, Echium amoenum, and Scutellaria lateriflora. Conclusion: Exploration of herbal plants may be beneficial to establish more potential compounds for treatment of anxiety disorders.

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Pharmacognostic Standardization of Cymbopogon citratus (dc.) stapf leaves

Shah¹,

Kaur²,

Dhabiliya³

et al. 2012

Pharmacognosy Journal

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2'-O-rhamnoside [10] and isolation of the flavonoids quercetin, kaempferol and apiginin [11] from aerial parts. The phenolic compounds elimicin, catecol, chlorogenic acid, caffeic acid and hydroquinone isolated from plant. [12] Various pharmacological activities of Cymbopogon citratus, have been reported such as Anti amoebic, [13] Antibacterial, [14-17] Antidiarrhoeal, [18] Antifungal, [19] Antimalarial, [20] Antiinflammatory [21] and Anti-anxiety. [22] Cymbopogon citrates (DC) Stapf (Graminae) (C. citratus) are an herb worldwide known as lemongrass. The tea made from its leaves is popularly used as antispasmodic, analgesic, anti-inflammatory, antipyretic, diuretic and sedative. [28] In lemongrass, antioxidant [29] , and antinociceptive [30] activities have been studied. A few ethno botanical reports on treatment of fever and headache were investigated. [23] MATERIALS AND METHODS

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Anti-anxiety Activity of Cymbopogon citratus (dc.) stapf Leaves Extracts on the Elevated Plus-Maze Model of Anxiety in Mice

Cited by 3 publications

References 17 publications

Neurobehavioral properties of Cymbopogon essential oils and its components

Neurobehavioral properties of Cymbopogon essential oils and its components

Overview on Phyto-based Treatment for Anxiety

Pharmacognostic Standardization of Cymbopogon citratus (dc.) stapf leaves

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