Anti-anxiety effect of methanol extract of &lt;i&gt;Pericarpium zanthoxyli&lt;/i&gt; using a strychnine-sensitive glycine receptor model

Kim, Tae Eun; Jung, Jung Hwa; Yoon, Saehee; Kim, Sungjin

doi:10.4314/tjpr.v15i5.8

Cited by 2 publications

(1 citation statement)

References 16 publications

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“…The mean number of steps climbed by the different treatment groups in this test shows no significant (P > 0.05) variation. This observation is in agreement with the findings in a previous study [29] whereby extract-treated and benzodiazepine-treated rodent groups exhibited no disparity (P > 0.05) in the number of stairs climbed compared to the negative control but had their rears significantly (P < 0.05) reduced to half the value obtained in the untreated (negative) controls.…”

Section: Discussionsupporting

confidence: 93%

Pharmacological Investigation of Serial Anxiety Tests in the Mouse: A Pilot Study

Umarudeen

Magaji

Bello

et al. 2020

JAMPS

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The use of test batteries has been suggested as a means to enhance throughput, to broaden the spectrum of anxiety parameters detectable and to minimise the numbers of experimental animals required in behavioural studies. This study was undertaken to determine the sensitivity of test batteries each of open field, zero mazes and staircase tests to anxiety behaviours in randomised mouse groups. Mice (n = 8) were exposed to these apparatuses serially in that order, thirty minutes following intraperitoneal administration of distilled water, 0.5 and 1.0 mg/kg diazepam. Each mouse was allowed to spend 5 minutes to freely explore each test apparatus. The results showed diazepam-treated mice exhibited significantly (p<0.05) reduced anxiety behaviours compared to the placebo group on most rodent anxiety parameters evaluated. The findings of this study suggest these behavioural test apparatuses, when used in serial combination, are sensitive and reliable to measure murine anxiety-related behaviours and the anxiolytic effects of standard/putative agents.

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Section: Discussionsupporting

confidence: 93%

Pharmacological Investigation of Serial Anxiety Tests in the Mouse: A Pilot Study

Umarudeen

Magaji

Bello

et al. 2020

JAMPS

View full text Add to dashboard Cite

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Overview on Phyto-based Treatment for Anxiety

Alambayan

Garg

2020

CPSP

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Background: Prevalence of psychiatric disorders such as anxiety is a very common and affecting many people all around the world. Currently, many synthetic pharmacological products/ drugs are available in the market to cure the disorder, but associated with various adverse reactions or side effects which may cause discomfort and sometimes other disorders to the patients. In the past years, use of complementary and alternative medicine has increased. The exploration in the areaof herbal psychopharmacology has received much attention as people are using more herbal treatment to benefit their health. Objective: To provide a comprehensive information on anxiety disorder and its herbal treatment Method: In this review, we enlisted the plants, plant extracts and isolated component (if any) along with models used to explore anxiolytic property; in retrospect, still a lot of research required to establish them clinically. Result: Literature revealed that a variety of medicinal plants are effective for the treatment of anxiety likeGinkgo biloba, Passiflora incarnata, Gelsemium sempervirens, Piper methysticum, Bauhinia variegate, Matricaria recutita, Brassica oleracea, Hypericum perforatum, Echium amoenum, and Scutellaria lateriflora. Conclusion: Exploration of herbal plants may be beneficial to establish more potential compounds for treatment of anxiety disorders.

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Anti-anxiety effect of methanol extract of <i>Pericarpium zanthoxyli</i> using a strychnine-sensitive glycine receptor model

Cited by 2 publications

References 16 publications

Pharmacological Investigation of Serial Anxiety Tests in the Mouse: A Pilot Study

Pharmacological Investigation of Serial Anxiety Tests in the Mouse: A Pilot Study

Overview on Phyto-based Treatment for Anxiety

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