2023
DOI: 10.21203/rs.3.rs-2646715/v1
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Anti-apoptotic effect of resveratrol: regulate of mitochondrial pathway in high tensile stress-induced goat temporomandibular joint disc cells

Abstract: Background: Attenuating of temporomandibular joint disc (TMJ disc) cells apoptosis may be an effective strategy to reduce abnormal stress-induced disc degeneration. However, a potential target to regulate the apoptosis of TMJ disc cells under abnormal stress is still inconclusive. Resveratrol (RSV) is a polyphenol with multiple effects such as anti-inflammatory, antioxidant, and anti-apoptosis. In this study, an appropriate periodic tensile stress was selected to induce apoptosis in goat TMJ disc cells. To exa… Show more

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