Anti-Atherosclerotic Activity of Elaeocarpus Ganitrus Roxb. In Cholesterol-Fed Rabbits

Jain, Preeti; Joshi, S. C.

doi:10.22159/ajpcr.2017.v10i12.20111

Cited by 5 publications

(3 citation statements)

References 29 publications

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“…In another significant study, Elaeocarpus ganitrus Roxb. extract treated rabbits showed significant protective effect by lowering the deposition of cholesterol and increasing the lumen size compared to cholesterolfed group [21].…”

Section: Puttaswamymentioning

confidence: 85%

Effect of Opuntia Elatior on Cholesterol Level Alterations Induced by Gamma Radiation in Swiss Albino Mice

Pooniam

Sharma

2019

Asian J Pharm Clin Res

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Objectives: Radiotherapy is deleterious to patient health by making the patient more susceptible to other diseases and often causes death by weakening the immune system and also affects cholesterol level. Based on these studies, it was moved toward the selection of Opuntia elatior as a herbal remedy for serum cholesterol level induced by gamma radiation. Methods: The modulatory effect of O. elatior stem extract was studied in Swiss albino mice at dose, i.e., 6 Gy of gamma radiation in the presence (experimental) or absence (control) of O. elatior extract (OEE) (10 mg/kg body weight) to observe in blood cholesterol level alterations. The animals were scarified and their blood was collected at days 1, 15, and 30 post-irradiation from heart puncture. Cholesterol level was estimated by the modified method of Roeschlau et al., 1974, using kit. Results: The cholesterol level was found almost constant in the control group (without any treatment) and increased in gamma radiation-treated group and decreased in only plant extract-treated group, whereas radiation-induced increased level of cholesterol was reduced by plant extract treatment in experimental animals (in plant extract with radiation-treated group), a normal level was achieved by day 30 post-treatment. Hence, O. elatior is beneficial to control radiation-induced blood cholesterol level. Conclusion: Radiation-induced side effects get lowered by herbal treatment and herbal products do not have their own side effects on body on their physical and chemical processes; thus, OEE is useful to manage blood cholesterol level as an edible part, it is easy to use as treatment and in my results OEE also support to maintain cholesterol level in serum of mice.

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Section: Puttaswamymentioning

confidence: 85%

Effect of Opuntia Elatior on Cholesterol Level Alterations Induced by Gamma Radiation in Swiss Albino Mice

Pooniam

Sharma

2019

Asian J Pharm Clin Res

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“…A high-fat diet, consisting of coconut oil and vanaspati ghee, in a ratio of 2:3 v/v at a dose of 10 ml/Kg body weight, was fed to the animals, orally, daily, in addition to the normal diet for a period of 8 weeks. 16,17…”

Section: Induction Of Hyperlipidemiamentioning

confidence: 99%

A Study of the Antihyperlipidemic and Antioxidant Activities of Ethanolic Extracts of Leaves of Houttuynia cordata Thunb . (EELHC) in Albino Rats

Tassa¹,

Sahu²,

Pathak³

2023

JOPCR

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The present study was designed to evaluate the antihyperlipidemic and antioxidant activities of leaves of Houttuynia cordata Thunb. The ethanolic extract was obtained by percolation method and acute oral toxicity tests were performed according to OECD (Organization for Economic Cooperation and Development) guidelines. Hyperlipidaemia was induced by feeding the rats with a high-fat diet consisting of coconut oil and vanaspati ghee, in a ratio of 2:3 v/v at a dose of 10 ml/Kg body weight. The extract was given at a dose of 500mg/kg body weight. Lipid profile, Malondialdehyde (MDA), Catalase (CAT), and Superoxide Dismutase (SOD) were measured using standard methods. The extract showed a significant decrease in total cholesterol, triglycerides, LDL, and MDA in the blood. On the other hand, HDL, CAT, and SOD increased significantly. The study demonstrates that the ethanolic extract of leaves of Houttuynia cordata Thunb., decreases blood lipid levels and lipid peroxidation. Keywords: Antihyperlipidemic, Antioxidant, Houttuynia cordata Thunb, EELHC

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“…-Total cholesterol was determined according to Jain et al, (2017). -HDL-C was determined according to Lopes et al, (1977).…”

Section: Lipid Patternsmentioning

confidence: 99%

Effect of Biscuits Supplemented with Cinnamon, Fennel, and Anise Powders on the Quality of Vital Functions in Aged Rats

Elsayed

Nagib

Mostafa

2023

Journal of Food and Dairy Sciences

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The objective of this work was to study the impact of 5% of cinnamon, fennel, and anise powder in biscuits on the quality of vital functions in 30 aged female rats, divided into 6 groups (5 rats) as following, group (1) young control group (-ve) fed on basal diet, group (2) elder control group (+ve) fed on basal diet, group (3) fed on wheat biscuit and the other groups 4, 5 and 6 were fed on cinnamon, fennel, and anise biscuits respectively during the experimental period (8 weeks). The results indicated that groups fed on biscuits supplemented with cinnamon, fennel, and anise powders showed significantly higher levels of serum HDLc , T.Bil, SOD, CAT,GSH ,calcium and hormones progesterone, and osteocalcin, while showed significantly lower level of serum TG, TC, LDL-c , VLDL-c , AST, ALT, ALP , creatinine, urea, uric acid, MDA, hormones LH, PTH, testosterone, comparing with elder control group (+ve). Therefore, the study recommends eating products that contain cinnamon, fennel and anise powder because they have antioxidant properties and can help treat cholesterol, liver, kidney and female hormones for the elderly.

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Anti-Atherosclerotic Activity of Elaeocarpus Ganitrus Roxb. In Cholesterol-Fed Rabbits

Cited by 5 publications

References 29 publications

Effect of Opuntia Elatior on Cholesterol Level Alterations Induced by Gamma Radiation in Swiss Albino Mice

Effect of Opuntia Elatior on Cholesterol Level Alterations Induced by Gamma Radiation in Swiss Albino Mice

A Study of the Antihyperlipidemic and Antioxidant Activities of Ethanolic Extracts of Leaves of Houttuynia cordata Thunb . (EELHC) in Albino Rats

Effect of Biscuits Supplemented with Cinnamon, Fennel, and Anise Powders on the Quality of Vital Functions in Aged Rats

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