Anti Bacterial Efficacy of  Terminalia  Chebula, Terminalia Bellirica, Embilica  Officinalis  and Triphala  on Salivary  Streptococcus Mutans  Count – A  Linear Randomized Cross Over Trial

Saxena, Smariti; Lakshminarayan, Nagesh; Gudli, Shanmukha; Kumar, Manish

doi:10.7860/jcdr/2017/23558.9355

Cited by 19 publications

(22 citation statements)

References 11 publications

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“…Another double-blind human clinical trial also reported significant reductions in oral streptococcus levels at 5 and 60 min after rinsing with 15 mL aqueous Triphala extract (10%) mouthwash. 47 …”

Section: Therapeutic Uses and Studiesmentioning

confidence: 99%

Therapeutic Uses ofTriphalain Ayurvedic Medicine

Peterson

Denniston

Chopra

2017

The Journal of Alternative and Complementary Medicine

262

156

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Aim: The aim of this article is to review the current literature on the therapeutic uses and efficacy of Triphala. Herbal remedies are among the most ancient medicines used in traditional systems of healthcare such as Ayurveda. Triphala, a well-recognized and highly efficacious polyherbal Ayurvedic medicine consisting of fruits of the plant species Emblica officinalis (Amalaki), Terminalia bellerica (Bibhitaki), and Terminalia chebula (Haritaki), is a cornerstone of gastrointestinal and rejuvenative treatment.Methods: A search of the PubMed database was conducted.Results: In addition, numerous additional therapeutic uses described both in the Ayurvedic medical literature and anecdotally are being validated scientifically. In addition to laxative action, Triphala research has found the formula to be potentially effective for several clinical uses such as appetite stimulation, reduction of hyperacidity, antioxidant, anti-inflammatory, immunomodulating, antibacterial, antimutagenic, adaptogenic, hypoglycemic, antineoplastic, chemoprotective, and radioprotective effects, and prevention of dental caries. Polyphenols in Triphala modulate the human gut microbiome and thereby promote the growth of beneficial Bifidobacteria and Lactobacillus while inhibiting the growth of undesirable gut microbes. The bioactivity of Triphala is elicited by gut microbiota to generate a variety of anti-inflammatory compounds.Conclusions: This review summarizes recent data on pharmacological properties and clinical effects of Triphala while highlighting areas in need of additional investigation and clinical development.

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Section: Therapeutic Uses and Studiesmentioning

confidence: 99%

Therapeutic Uses ofTriphalain Ayurvedic Medicine

Peterson

Denniston

Chopra

2017

The Journal of Alternative and Complementary Medicine

262

156

View full text Add to dashboard Cite

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“…Health protective (Razi, 1991) Oral (Razi, 1991) Anti-inflammatory, anti-oxidant, immunomodulatory (Isik et al, 2019) Tannins, terpenes, flavonoids, organic acids (Abu-Reidah, Ali- (Rushd, 1987) Oral (Rushd, 1987) Anti-inflammatory, analgesic (Rushd, 1987) Oral (Rushd, 1987) Hepatoprotective (Jung et al, 2019), neuroprotective (Shen, Juan, Lin, Chen, & Chang, 2017), anti-bacterial (Saxena, Lakshminarayan, Gudli, & Kumar, 2017) Chebulic acid (Jung et al, 2019), tannins, triterpenoids (Shen et al, 2017), gallic acid (Saxena et al, 2017) Vinegar…”

Section: Sum Aqmentioning

confidence: 99%

Exploring new horizons in health care: A mechanistic review on the potential of Unani medicines in combating epidemics of infectious diseases

Fazil

Nikhat

2020

Phytotherapy Research

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“…Triphala is composed of the fruits of three herbal plant trees, Phyllanthus emblica L. (Amla), Terminalia belerica Retz., and Terminalia chebula Retz (21). It possesses anti-inflammatory (22), antimicrobial (23), antiulcer (24), antiviral, and antibacterial (25) properties. Even though Triphala has a long history in many different therapeutic applications in PTM and ayurvedic medicine such as the treatment of digestive disorders (21)(22)(23)(24)(25)(26), its combination with Coriander (as Coriander Triphala) is unique to PTM.…”

Section: Introductionmentioning

confidence: 99%

Effects of Pistacia lentiscus and Coriander Triphala on Adult Gastroesophageal Reflux Disease: A Randomized Double-Blinded Clinical Trial

Sadeghi

Fazljou

Sepehri

et al. 2020

Iran Red Crescent Med J

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Background: The cardinal symptoms of gastroesophageal reflux disease include heartburn (pyrosis) and regurgitation. Conventional treatment is done by proton pump inhibitors. In Persian traditional medicine, several herbs (single or combined) have been used to treat gastrointestinal disorders. Objectives: This study aimed to assess the effects of Pistacia lentiscus (mastic) and Coriander Triphala on reflux symptoms compared to omeprazole in a double-blinded randomized clinical trial. Methods: In a double-blinded, multicenter, randomized clinical trial, we assessed the effects of Pistacia lentiscus L., Coriander Triphala, and omeprazole on the symptoms of GERD in Tabriz, Iran, in 2018 - 2019. Thus, 105 patients with GERD symptoms were assigned randomly to three groups as group A (Pistacia lentiscus L., 1000 mg/TDS), group B (Coriander Triphala, 1000 mg/TDS), and group C (omeprazole, 20 mg/day plus five placebo capsules per day). The assessments were done at the beginning and the end of the study using FSSG, VAS, RS, and GERD-HRQL questionnaires. Results: In the beginning, no significant differences were observed between the groups in the background characteristics. There was no statistically significant difference between Pistacia lentiscus, Coriander Triphala, and omeprazole in the improvement of FSSG, VAS, GERD-HRQL, and reflux scores. In all groups, the FFSG, VAS, reflux, and GERD-HRQL scores significantly decreased and improved after four weeks of intervention compared to the respective baselines. The FSSG score improvements after four weeks of intervention were 73.68%, 83.33%, and 68.62%, in groups A, B, and C, respectively. The VAS score improvements were 66.66%, 75.00%, and 62.50% in groups A, B, and C, respectively. Improvements in GERD-HRQL were 90.00%, 91.28%, and 82.00%, in groups A, B, and C, respectively. Reflux improvements were 66.66%, 80.00%, and 66.66% in groups A, B, and C, respectively. Conclusions: The results showed that Pistacia lentiscus and Coriander Triphala are as effective as omeprazole in the treatment of GERD.

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Anti Bacterial Efficacy of Terminalia Chebula, Terminalia Bellirica, Embilica Officinalis and Triphala on Salivary Streptococcus Mutans Count – A Linear Randomized Cross Over Trial

Cited by 19 publications

References 11 publications

Therapeutic Uses ofTriphalain Ayurvedic Medicine

Therapeutic Uses ofTriphalain Ayurvedic Medicine

Exploring new horizons in health care: A mechanistic review on the potential of Unani medicines in combating epidemics of infectious diseases

Effects of Pistacia lentiscus and Coriander Triphala on Adult Gastroesophageal Reflux Disease: A Randomized Double-Blinded Clinical Trial

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