Anti candidal efficacy of commercially available triphala, neem, denture cleanser and natural aloevera leaf on heat polymerized acrylic resin

Ojah, Polysmita; Luniyal, Chetan; Nair, Chandana; Astekar, Madhusudan; Pal, Ankita; Chopra, Megha

doi:10.4103/jips.jips_599_20

Cited by 5 publications

(1 citation statement)

References 16 publications

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“…A recent study by Nair et al showed that aloe vera had the least antifungal activity when compared to the conventional denture cleansers, neem and triphala. In the current study, while comparing the mean reduction in candida count between the three groups, aloe vera was shown to be more effective than chitosan and the control group [ 36 ].…”

Section: Discussionmentioning

confidence: 99%

Effectiveness of Chitosan versus Natural Aloe Vera on Candida Adherence in Denture Soft Lining Material

Memon,

Shoro

et al. 2024

Scientifica

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Background. Soft denture lining materials act as a cushion between the denture base and tissues. Alongside having many advantages, its main problem is candida growth due to its rubbery and porous texture. Many interventions have been performed to halt the growth of candida within soft lining materials such as the use of antifungal therapy and strict oral and denture hygiene but there are consequences such as recurrence, drug resistance, and toxicity related to these interventions. Since natural agents such as aloe vera and chitosan have been proven to have antibacterial and antifungal properties with minimum adverse effects, this study aimed to study the effectiveness of chitosan and aloe vera powders incorporated within denture soft lining materials against candida adherence. Methodology. A total of 60 soft-lining material samples were prepared that were equally divided into three groups, viz., group 1 (chitosan incorporation), group 2 (aloe vera incorporation), and group 3 (control). Candida was obtained from the microbiology lab to form a candidal suspension, diluted in 0.9% NaCl to match the McFarland standard bacteriologic solution. Samples were incubated at 37°C for 24 hours in test tubes containing 100 mL of the candidal suspension and 9.9 mL of the previously prepared Sabouraud dextrose agar. Crystal violet stain was used to stain the adhering cells by fixing them with methanol 80%. For each sample, the adhering candida cells were counted on three standard fields by using an inverted light microscope, and the mean of those fields was recorded. Results. The mean value for samples containing aloe vera was 41.15, while the mean values for samples containing chitosan and the control group were 16.05 and 79.1, respectively. Of all the three groups, aloe vera powder had a significant efficacy against candida growth as compared to the chitosan and control groups (P value = 0.001). Conclusion. Both herbal agents were effective against candida growth. In comparison, aloe vera was more effective against candida growth compared to chitosan.

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Section: Discussionmentioning

confidence: 99%

Effectiveness of Chitosan versus Natural Aloe Vera on Candida Adherence in Denture Soft Lining Material

Memon,

Shoro

et al. 2024

Scientifica

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Aloe Vera and Oral Health

Pentapati,

Siddiq,

Abhinav

2023

Pharmacological Studies in Natural Oral Care

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Natural products for denture base disinfection: A scoping review

de Lima,

Santiago,

Avelino

et al. 2024

Gerodontology

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ObjectiveThis study aims to map the existing literature on natural products used as disinfection substances for conventional polymethyl methacrylate (PMMA) and computer‐aided design and manufacturing (CAD‐CAM) dentures.BackgroundDenture wearers are at high risk for denture stomatitis. Natural products have attracted the interest of the scientific community as an alternative to synthetic ones.Materials and methodsThe guiding question “Which natural products have been applied to disinfect complete dentures in conventional PMMA or CAD‐CAM PMMA resin?” Searches were conducted in the PubMed/MEDLINE, Embase, Web of Science, and Cochrane databases, and manual searches were performed in reference journals in the area with studies published until December 2023, without language or date restrictions.ResultsA total of 4272 articles were identified, and 46 studies were included after applying the eligibility criteria. Thirty‐nine natural products were evaluated. Of the included studies, 43 presented positive findings and three obtained negative findings on the effectiveness of natural products in inhibiting or killing Candida albicans.ConclusionNatural products, predominantly sourced from the Plantae kingdom, have demonstrated efficacy in reducing Candida albicans on the surface of conventional PMMA. However, the evidence primarily stems from in vitro studies, underscoring the necessity for additional clinical research to validate their applicability under real microbiological conditions in prosthesis users.

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Anti candidal efficacy of commercially available triphala, neem, denture cleanser and natural aloevera leaf on heat polymerized acrylic resin

Cited by 5 publications

References 16 publications

Effectiveness of Chitosan versus Natural Aloe Vera on Candida Adherence in Denture Soft Lining Material

Effectiveness of Chitosan versus Natural Aloe Vera on Candida Adherence in Denture Soft Lining Material

Aloe Vera and Oral Health

Natural products for denture base disinfection: A scoping review

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