Anti-demineralization effect of desensitizer containing copolymer and sodium fluoride on root dentin – a transverse microradiographic study

Abstract

Objective: To evaluate anti-demineralization effects of dentin desensitizer containing sodium fluoride and methacrylate-co-p-styrene sulfonic acid (MS polymer) on root dentin using transverse microradiography (TMR).Material and methods: Twenty-four dentin specimens were divided into four groups: MSO (no fluoride), MSF (3000 ppm F), FJL (9000 ppm F), and Control. In MSO and MSF, each desensitizer was rubbed into the dentin surfaces for 10 s then left for 20 s. In FJL, paste containing 9000 ppm F was applied onto the surface for 30 s. All specimens, including the Controls, were rinsed with deionized water, dried and an area of their surface exposed to pH 5.0 acidic solution, refreshed every 24 h, for 4 days. Sections 300-µm-thick were assessed by TMR. Mineral profiles and integrated mineral loss (IML) of lesions were analyzed by dedicated software. IML was analyzed with one-way ANOVA and Tukey’s test.Results: MSF and FJL specimens showed high mineral volume % at the surface and in lesions, and significantly lower IML than the other groups (p < .05).Conclusion: Dentin desensitizer containing 3000 ppm fluoride and MS polymer has the same anti-demineralization effect as does a fluoride paste containing 9000 ppm F.

Remineralizing Ability of Resin Composite Incorporating Calcium Phosphate Nanoparticles and Fluoride Containing Adhesive.

“…Poly (amidoamine) (PAMAM) and rechargeable composite incorporating nanoparticles of calcium phosphate (NACP) have also been reported to achieve dentin remineralization completely and restore the hardness similar to healthy dentin, so that PAMAM plus recharged NACP remineralized predemineralized dentin completely, with prolonged fluid challenge like to the oral environment (18) . Moreover, it was suggested that dentin desensitizer containing 3000ppm fluoride and methacrylate-cop-styrene sulfonic acid (MS polymer) has the same anti-demineralization effect on root dentin lesion as does a fluoride paste containing 9000ppm F (19) . Furthermore, it was reported that fluoride dentifrice was capable to hamper further demineralization of sound dentin as well as lowly and highly demineralized dentin artificial caries (20) .…”

Anti-demineralization characteristics of surface pre-reacted glass-ionomer (S-PRG) filler-containing varnishes

“…Dentin specimens were prepared as described 15,17,18) . The experimental procedures are outlined in Fig.…”

Effects of desensitizer containing fluoroaluminocalciumsilicate glass nanoparticles on remineralization of root dentin subsurface lesions <i>in vitro </i>

“…A scan of each section was performed at the center of the lesion, and values were calculated for three parameters: mineral content profile, integrated mineral loss (IML: vol%×µm), and lesion depth (LD: µm). The values of two sections from each specimen were averaged 4,29,30) .…”

“…While such demineralization includes both bacterial and nonbacterial agents, desensitizers with remineralization ability would be useful. Although anti-demineralization effects of desensitizers have been studied [3][4][5] , no study has reported the remineralizing effects of desensitizers using transverse microradiography (TMR) in predemineralized root dentin. TMR, which reveals precise levels of mineral loss, is widely recognized as the gold standard method in demineralization and remineralization studies of both enamel and dentin [6][7][8] .…”