Anti-dermatophyte activity of Leguminosae plants from Southern Brazil with emphasis on Mimosa pigra (Leguminosae)

Morais, Cláudia Borges de; Scopel, Marina; Pedrazza, Graziele Pereira Ramos; Silva, F.K. da; Lana, Daiane Flores Dalla; Tonello, Monica Lopes; Miotto, Sílvia T. S.; Machado, Michel Mansur; Oliveira, Luís Flávio Souza de; Fuentefria, Alexandre M.; Zuanazzi, José Ângelo Silveira

doi:10.1016/j.mycmed.2017.07.006

Cited by 12 publications

(4 citation statements)

References 25 publications

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“…Both plant extracts were found to be active against P. aeruginosa , C. albicans , S. aureus , and B. subtilis and inactive against E. coli and A. niger. De Morais et al [ 147 ] determined the antifungal activity of 60% MeOH, DCM, and EtOAc fractions of M. pigra leaves by measuring the minimum inhibitory concentration (MIC) values against dermatophyte strains ( T. mentagrophytes , E. floccosum , M. gypseum , and T. rubrum ). The MeOH extract showed the lowest MIC values against all dermatophytes (1.9 to 1000 mg/mL).…”

Section: Pharmacological Activities Of Genus Mimosamentioning

confidence: 99%

A Comprehensive Review of the Ethnotraditional Uses and Biological and Pharmacological Potential of the Genus Mimosa

Majeed

Ashar

Rasheed

et al. 2021

IJMS

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The Mimosa genus belongs to the Fabaceae family of legumes and consists of about 400 species distributed all over the world. The growth forms of plants belonging to the Mimosa genus range from herbs to trees. Several species of this genus play important roles in folk medicine. In this review, we aimed to present the current knowledge of the ethnogeographical distribution, ethnotraditional uses, nutritional values, pharmaceutical potential, and toxicity of the genus Mimosa to facilitate the exploitation of its therapeutic potential for the treatment of human ailments. The present paper consists of a systematic overview of the scientific literature relating to the genus Mimosa published between 1931 and 2020, which was achieved by consulting various databases (Science Direct, Francis and Taylor, Scopus, Google Scholar, PubMed, SciELO, Web of Science, SciFinder, Wiley, Springer, Google, The Plant Database). More than 160 research articles were included in this review regarding the Mimosa genus. Mimosa species are nutritionally very important and several species are used as feed for different varieties of chickens. Studies regarding their biological potential have shown that species of the Mimosa genus have promising pharmacological properties, including antimicrobial, antioxidant, anticancer, antidiabetic, wound-healing, hypolipidemic, anti-inflammatory, hepatoprotective, antinociceptive, antiepileptic, neuropharmacological, toxicological, antiallergic, antihyperurisemic, larvicidal, antiparasitic, molluscicidal, antimutagenic, genotoxic, teratogenic, antispasmolytic, antiviral, and antivenom activities. The findings regarding the genus Mimosa suggest that this genus could be the future of the medicinal industry for the treatment of various diseases, although in the future more research should be carried out to explore its ethnopharmacological, toxicological, and nutritional attributes.

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Section: Pharmacological Activities Of Genus Mimosamentioning

confidence: 99%

A Comprehensive Review of the Ethnotraditional Uses and Biological and Pharmacological Potential of the Genus Mimosa

Majeed

Ashar

Rasheed

et al. 2021

IJMS

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“…Potentially phytotoxic substances in certain plants has been investigated, even allowing the extraction of these compounds for application against weeds in agriculture (Dayan et al, 2012). When evaluating the crude methanolic extract of M. pigra for fungicidal action, De Morais et al (2017) identified flavonoid heterosides and aglycones as possible substances responsible for the antifungal activity. In addition, the authors reported that toxicogenetic studies for this specimen are still scarce.…”

Section: Resultsmentioning

confidence: 99%

Research Article Toxicogenetic potential of Mimosa pigra (Fabaceae) infusion in Allium cepa meristematic cells

Araújo¹,

Santos²,

Barros-Filho³

et al. 2020

Genet. Mol. Res.

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Mimosa pigra is a plant commonly used for medicinal purposes in the treatment of several diseases. However, studies regarding its toxicological properties are scarce. We evaluated the toxic, cytotoxic, genotoxic and mutagenic activities of leaf and stem infusions of M. pigra collected in the region of Delta do Parnaíba, Piauí, Brazil, through an in vivo Allium cepa test. Three concentrations of leaf and stem treatments were used (leaf treatment 1 and stem treatment 1 = 0.771 g/L; leaf treatment 2 and stem treatment 2 = 1.542 g/L; leaf treatment 3 and stem treatment 3 = 3.084 g/L), in addition to the negative controls (water) and positive controls (copper sulfate-1.2 mg/mL-A. cepa test). All the treatments were toxic, causing significant root growth inhibition. Leaf treatment 1, leaf treatment 3 and stem treatment 1 showed significant inhibition of the mitotic index. Leaf treatment 2, stem treatment 1 and stem treatment 3 showed significant genotoxic activity based on the frequency of chromosomal aberrations. The tested concentrations did not provoke significant mutagenic activity ©FUNPEC-RP www.funpecrp.com.br Genetics and Molecular Research 19 (3): gmr18588 M.S. Araújo et al. 2 when compared to the negative control. We suggest that further studies with other biological systems are needed to evaluate the safetyness of M. pigra infusions for therapeutic purposes.

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“…Pharmacological investigations showed that M. pigra contains several secondary metabolites, which have pharmacological activity such as analgesic, antipyretic, anti-inflammatory, anti-diabetic, anticancer and antioxidant activity [ 104 , 105 , 106 ]. The methanol extracts of M. pigra leaves showed antioxidant and anti-inflammatory actions in the Wister rat, and quercitrin (quercetin 3- O -rhamnoside) and myricitrin (myricetin 3- O -rhamnoside) were isolated from the extracts [ 104 ] ( Figure 3 ).…”

Section: Invasive Mechanismmentioning

confidence: 99%

“…The methanol extracts of M. pigra leaves showed antioxidant and anti-inflammatory actions in the Wister rat, and quercitrin (quercetin 3- O -rhamnoside) and myricitrin (myricetin 3- O -rhamnoside) were isolated from the extracts [ 104 ] ( Figure 3 ). The methanol extracts of M. pigra leaves also showed anti-dermatophyte activity, and astragalin, luteolin and quercitrin were isolated from the extracts [ 105 ].…”

Section: Invasive Mechanismmentioning

confidence: 99%

Invasive Mechanisms of One of the World’s Worst Alien Plant Species Mimosa pigra and Its Management

Kato‐Noguchi

2023

Plants

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Mimosa pigra is native to Tropical America, and it has naturalized in many other countries especially in Australia, Eastern and Southern Africa and South Asia. The species is listed in the top 100 of the world’s worst invasive alien species and is listed as Least Concern in the IUCN Red List of Threatened Species. M. pigra forms very large monospecific stands in a wet–dry tropical climate with conditions such as floodplains, riverbanks, grasslands, forests and agricultural fields. The stands expand quickly and threaten the native flora and fauna in the invasive ranges. Possible mechanisms of the invasion of the species have been investigated and accumulated in the literature. The characteristics of the life history such as the high reproduction and high growth rate, vigorous mutualism with rhizobia and arbuscular mycorrhizal fungi, very few natural enemies, and allelopathy, and certain secondary metabolites may contribute to the invasiveness and naturalization of M. pigra. Herbicide application, such as aerial spraying, foliar, cut-stump and soil treatments, is the primary control methods of M. pigra. The investigation of the natural enemies of M. pigra has been conducted in its native ranges since 1979, and biological control agents have been selected based on host specificity, rearing and availability. Mechanical control practices, such as hand weeding, bulldozing, chaining and fire, were also effective. However, the species often regrow from the remaining plant parts. Integration of multiple weed control practices may be more effective than any single practice. This is the first review article focusing on the invasive mechanism of M. pigra.

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Anti-dermatophyte activity of Leguminosae plants from Southern Brazil with emphasis on Mimosa pigra (Leguminosae)

Cited by 12 publications

References 25 publications

A Comprehensive Review of the Ethnotraditional Uses and Biological and Pharmacological Potential of the Genus Mimosa

A Comprehensive Review of the Ethnotraditional Uses and Biological and Pharmacological Potential of the Genus Mimosa

Research Article Toxicogenetic potential of Mimosa pigra (Fabaceae) infusion in Allium cepa meristematic cells

Invasive Mechanisms of One of the World’s Worst Alien Plant Species Mimosa pigra and Its Management

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