Anti diabetic agents

Dual active pyrimidine-based carbocyclic nucleoside derivatives: synthesis, and in silico and in vitro anti-diabetic and anti-microbial studies

“…[6][7][8] a-Glucosidase inhibitors are used to treat type 2 diabetes by slowing the absorption of carbohydrates in the small intestine. 9 These inhibitors have multiple advantages in controlling diabetes, including delayed digestion of complex carbohydrates, slowing glucose release, reducing postprandial hyperglycemia, and regulating postprandial glucose levels. 3,6 Typically used alongside other anti-diabetic medications or insulin therapy, aglucosidase inhibitors can enhance a diabetes management plan and are rarely used as initial treatments (Fig.…”