2024
DOI: 10.1002/cbdv.202401575
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Anti‐Diabetic and Insulinotropic Effects of p‐Anisic Acid in High‐Fat Diet and Streptozotocin Induced Type‐2 Diabetic Rats

Vishal Vora,
Pravin Tirgar,
Keval Raval

Abstract: Purpose: To evaluate the antidiabetic effect of p‐anisic acid (p‐AA) against type 2 diabetes mellitus (T2DM). Methods: Thirty‐six male rats were utilized for the study. The animals were provided with the high‐fat diet (HFD) and T2DM was induced through 35 mg/kg streptozotocin (STZ). Subsequently, the animals were allocated to 6 groups and subjected to the treatments for 4 weeks followed by a 2‐week observation. Three treatment groups were administered with p‐AA (25 mg/kg, 50 mg/kg or 100 mg/kg). Glibenclamide … Show more

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