2014
DOI: 10.1039/c3fo60366k
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Anti-diabetic effects of the Indian indigenous fruit Emblica officinalis Gaertn: active constituents and modes of action

Abstract: Dietary constituents are shown to play an important role in the development of diabetes. Studies have shown that the fruits of Emblica officinalis Gaertn or Phyllanthus emblica Linn, colloquially known as Indian gooseberry or amla and/or some of its important constituents (including gallic acid, gallotanin, ellagic acid and corilagin), possess anti-diabetic effects through their antioxidant and free radical scavenging properties. Amla has also been reported to prevent/reduce hyperglycemia, cardiac complication… Show more

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Cited by 84 publications
(39 citation statements)
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“…Gallic acid is a phytochemical, which has been isolated from several plants such as Emblica officinalis Gaertn [23], Phaleria macrocarpa Boerl [24], Quercus robur [25], and Castanea sativa L. [26] and has anti-fungal [9], anti-viral [10], antioxidant [11] properties. However, gallic acid is thermally unstable [27], which makes its use as cosmetic ingredient difficult.…”
Section: Discussionmentioning
confidence: 99%
“…Gallic acid is a phytochemical, which has been isolated from several plants such as Emblica officinalis Gaertn [23], Phaleria macrocarpa Boerl [24], Quercus robur [25], and Castanea sativa L. [26] and has anti-fungal [9], anti-viral [10], antioxidant [11] properties. However, gallic acid is thermally unstable [27], which makes its use as cosmetic ingredient difficult.…”
Section: Discussionmentioning
confidence: 99%
“…Phyllanthus emblica or Emblica officinalis, commonly known as amla or amlaki is an important traditional medicinal fruit in Ayurveda medicine, which has been used for the treatment of a wide variety of diseases including diabetes. Experimental studies revealed that P. emblica exhibits several pharmacological properties including anti-inflammatory, hepatoprotective, anti-hyperlipidemic, neuroprotective, nephroprotective and cardioprotective activities (D'Souza et al, 2014;Krishnaveni et al, 2010). Its methanolic extract showed an antihyperglycemic effect on alloxan-induced diabetic rats.…”
Section: Phyllanthus Emblica (Phyllanthaceae)mentioning
confidence: 99%
“…For example, curcumin is a major component of turmeric known to exhibit anti-inflammatory, antitumor, and antioxidant properties [19]. Similarly, gallic acid, gallotannin, ellagic acid, and corilagin are some of the important constituents of amla and are also reported to possess several medicinal properties, for example, cardioprotective, gastroprotective, chemopreventive, anti-inflammatory, antimutagenic and also free radical scavenging, and antioxidant [26, 27]. …”
Section: Introductionmentioning
confidence: 99%