Anti-diabetic potential of Ficus racemosa: current state and prospect especially in the developing countries

Amin, M. M.; Bhakta, Santanu; Das, Swarnamoni

doi:10.18801/jbar.050215.56

Cited by 9 publications

(5 citation statements)

References 17 publications

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“…The second highest F IC value (0.87%) was calculated for endocrine disorder category, which included the reported use of Coccinia grandis, Ficus racemosa, and Syzygium cumini. These three plant species have anti-diabetic property [34][35][36][37][38][39]. The similar F IC value (0.85%) was exhibited by cardiovascular and respiratory system disorders.…”

Section: Use Reports and F Icmentioning

confidence: 99%

Ethnomedicinal Study of Plants in Begumgonj, Noakhali, Bangladesh

Akter

Sajib²,

Kang

et al. 2021

Preprint

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Backgraound: The aim of this study was to document and preserve the ethnomedicinal knowledge used by traditional healers of Begumganj upazila, Bangladesh, to treat human diseases and evaluate the relative efficacy of the medicinal plants.Methods: The uses of medicinal plants were documented as an ethnomedicinal data sheet using direct observation, field interview, plant interview and group interview techniques from December 2012 to January 2014 in the study area. Data were collected from 98 traditional healers through a questionnaire survey and analyzed through informant consensus factor and fidelity level.Results: Overall, 75 plant species under 71 genera of 47 families were documented, which are used to treat 41 diseases. Data analysis revealed that 41.33%, 14.67%, 36% and 8% of the medicinal plant species were herbs, shrubs, trees, and climbers, respectively. Leaves were the most used parts, followed by stem, root, fruit, bark, latex and rhizome. The most frequently treated diseases were dysentery, rheumatism and skin diseases.Conclusions: This is the first ethnobotanical survey, which recorded the importance of medicinal plants in Begumgonj upazila, Bangladesh. This study can contribute to preserving the indigenous knowledge on the traditional use of medicinal plants in this region and attract future generations towards traditional healing practice.

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Section: Use Reports and F Icmentioning

confidence: 99%

Ethnomedicinal Study of Plants in Begumgonj, Noakhali, Bangladesh

Akter

Sajib²,

Kang

et al. 2021

Preprint

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show abstract

“…[84] The fruit, bark, latex, seeds, or leaves of F. racemosa plant have been reported to decrease blood glucose levels in diabetic animals. [85] IDDM: Insulin-dependent diabetes mellitus, NIDDM: Hypoglycemic activity, inhibit glucose uptake in the intestine. Stimulate insulin secretion from mouse cells and isolated human islets in vitro, lowered fasting blood glucose, release insulin probably by causing regeneration of pancreatic β-cells both in vivo and in vitro.…”

Section: Unani Name Botanical Name Antidiabetic and Other Favorable Amentioning

confidence: 99%

Unani Formulations for Management of Diabetes: An Overview

Hamiduddin¹

2018

IJGP

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Diabetes is a leading cause of death. In India, total number of diabetic patients is expected to be 79.4 million in 2030. It is a multifactorial disease leading to several complications. Traditional medicines are being looked up once again for its treatment; the WHO also recommended its further investigation. In this review, these drug its pharmacological activity and its formulation in Greco-Arab or Unani Medicine in India is explored. Singledrug used in formulation with reported anti-diabetic and related beneficial property are Gymnema sylvestre, Azadirachta indica, Aloe vera, Momordica charantia, Acacia arabica, Eugenia jambolana, Trigonella foenum graecum, Punica granatum, etc. Phytomedicine used in Unani medicine presents an exciting opportunity for the development of new types of therapeutics for diabetes mellitus with a holistic approach, which includes various photochemical groups such as alkaloids, terpenes, and phenolics. Beside hypoglycemic activity, these drugs also have antioxidants, bitter and other activity related to disturbance in carbohydrate metabolism. They are used in the form of decoctions, infusions, tablets, pills, and powder such as Qurse Dhayabitus, Qurse Tabasheer, Safoof Gilo, Qurse Marwareed, Qurse Gulnar, Dawaul Misk Talkh, Sharbate Afsanteen, Roghane Qusht, and Ma-Usshaeer and common marketed formulation is Dolabi tablets, Qurs Kushta baiza murgh, Qurs Kushta Zamarrud, Qurs Ziabetus, Safoof Ziabtes, Diab-eaze, etc. There is the tremendous scope of Unani single and compound formulations in the comprehensive management of diabetes particularly Type-2 diabetes; it can also be utilized as an adjuvant with the conventional drug due to its diverse and related beneficial pharmacological activity in diabetes.

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“…As about 50% of the Bangladeshi populations are at risk of diabetes each year, the majority of people especially in rural areas, use herbal medicine alone or alongside prescription drugs for diabetes management (Amin et al, 2015). Experimental models play an important role in understanding such a disease, which is treatable only.…”

Section: Phytochemical Processing Of Raw Plant Materials Is Essentiallymentioning

confidence: 99%

Copacetic herbal extraction techniques and diabetes induction methods for developing countries

Amin¹,

Das²

2016

J. biosci. agric. res.

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Extraction is an empirical exercise for the discovery of bioactive constituents from the plant materials. Selection of a suitable extraction technique is also important for the standardization of herbal products and to eliminate unwanted material by treatment with a selective solvent known as "menstrum". Traditional conventional methods such as maceration, rotary evaporation, soxhelation, percolation, lyophilization, infusion, decoction etc are more cheap and appropriate for developing countries rather than fast and environmentally friendly green extraction techniques like ultrasound assisted solvent extraction, microwave assisted solvent extraction and supercritical fluid extractions for phytochemical processing of medicinal plants. Moreover, plant-derived phytochemicals have established their role for possible use in diabetes treatment which is the world's largest endocrine disease associated with increased morbidity and mortality rate. Several experimental models are used to study pathophysiological factors involved in diabetes and to assess the efficacy of herbal antihyperglycemic agents. Today different strains of laboratory animals are available and therapeutic studies on diabetes are mostly carried out on these models. In animals, it can be induced by partial pancreatectomy or by the administration of diabetogenic drugs such as alloxan, streptozotocin, ditizona and anti-insulin serum. Hence, the review is aiming to draw attention of the relevant researchers to the convenient use of suitable extraction technique and diabetogenic drugs for developing countries.

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Anti-diabetic potential of Ficus racemosa: current state and prospect especially in the developing countries

Cited by 9 publications

References 17 publications

Ethnomedicinal Study of Plants in Begumgonj, Noakhali, Bangladesh

Ethnomedicinal Study of Plants in Begumgonj, Noakhali, Bangladesh

Unani Formulations for Management of Diabetes: An Overview

Copacetic herbal extraction techniques and diabetes induction methods for developing countries

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