Anti-hepatitis B virus activity of Boehmeria nivea leaf extracts in human HepG2.2.15 cells

Abstract

Abstract. Boehmeria nivea (Linn.) Gaudich of the Urticaceae family is a perennial ratoon herbal plant, the root of which is used in traditional Chinese medicine and possesses a variety of pharmacological properties. The 20% ethanol Boehmeria nivea root extract was shown to exert an anti-hepatitis B virus (HBV) effect in vitro and in vivo; however, whether the Boehmeria nivea leaf (BNL) extract possesses similar properties has not been determined. In this study, we aimed to investigate the anti-HBV effects of the BNL extract in HepG2.

Extract of Boehmeria nivea Suppresses Mast Cell-Mediated Allergic Inflammation by Inhibiting Mitogen-Activated Protein Kinase and Nuclear Factor-κB

“…Gaudich is a plant in the nettle family Urticaceae, native to eastern Asia. This plant is used in traditional Chinese herbal medication and possesses various pharmacological properties [ 5 ]. The leaves are commonly used for treating wounds, while the roots are used in the treatment of colic in pregnancy, impetigo, threatened abortions, and leucorrhoea.…”

“…The leaves are commonly used for treating wounds, while the roots are used in the treatment of colic in pregnancy, impetigo, threatened abortions, and leucorrhoea. The leaves in Boehmeria nivea contain numerous physiological active components, such as flavonoids, vitamins, minerals, rutin, and carotenoids, and have been found to exert a wide range of anti-inflammatory [ 6 , 7 ], anti-viral [ 5 ], anti-bacterial [ 8 ], anti-tumor [ 9 ], and anti-oxidant effects [ 10 , 11 ]. Despite the benefits of Boehmeria nivea and its potential use in various treatments, its underlying mechanism and effects on allergic reactions are unidentified.…”

Effect of Boehmeria nivea on Adipocyte Differentiation and Angiogenesis

“…모시풀 [Boehmeria nivea (Linn.) Gaudich (Urticaceae)]은 주 로 모시옷을 만들기 위해 재배되어 왔지만, 민간에서는 오랜 기간 동안 모시잎을 떡을 만들거나 나물로서 섭취해왔다 [9]. 또한 전통적으로 저장 식품의 곰팡이 억제에 사용되어져 왔 으며, 상처치료에 사용되어져 왔다 [9,10].…”

“…Gaudich (Urticaceae)]은 주 로 모시옷을 만들기 위해 재배되어 왔지만, 민간에서는 오랜 기간 동안 모시잎을 떡을 만들거나 나물로서 섭취해왔다 [9]. 또한 전통적으로 저장 식품의 곰팡이 억제에 사용되어져 왔 으며, 상처치료에 사용되어져 왔다 [9,10]. 최근 본 연구진을 통해 모시풀은 세포모델에서 lipopolysaccharide (LPS)에 의 해 유도되는 proinflammatory 사이토카인인 TNF-α와 IL-6의 발현 억제가 p38과 c-Jun N-terminal kinase (JNK) 단백질 억 제를 통해서 이루어짐이 밝혀졌다 [11].…”

Advance in studies on traditional Chinese medicines to treat infection with the hepatitis B virus and hepatitis C virus

“…A study by Dai et al, isolated 13 bioactive compounds from the TCM Viola diffusa Ging, and results suggested that 2β-hydroxy-3,4-seco-friedelolactone-27-oicacid,2β, 28β-dihydroxy-3,4-seco-friedelolactone-27-oicacid, and 2β,30β-dihydroxy-3,4-seco-friedelolactone- (16).…”