2008
DOI: 10.1002/14651858.cd005604.pub3
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Anti-histamines for prolonged non-specific cough in children

Abstract: Anti-histamines for prolonged non-specific cough in children.

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Cited by 27 publications
(15 citation statements)
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“…However, three studies evaluating nocturnal cough in children with URTI did not demonstrate a beneficial effect of diphenhydramine compared with placebo (Paul et al, 2004a;Yoder et al, 2006) or honey (Shadkam et al, 2010). A recent Cochrane Database Systematic Review concluded that, based on available data, H1-receptor antagonists cannot be recommended for the treatment of acute or chronic cough in children (Chang et al, 2008). The fairly common usage of H 1 -antihistamines for the treatment of cough in adults, albeit based on decades of clinical experience, overall is not supported by adequately performed clinical trials clearly demonstrating their effectiveness.…”
Section: Drugs In Current Use For the Treatment Of Coughmentioning
confidence: 99%
“…However, three studies evaluating nocturnal cough in children with URTI did not demonstrate a beneficial effect of diphenhydramine compared with placebo (Paul et al, 2004a;Yoder et al, 2006) or honey (Shadkam et al, 2010). A recent Cochrane Database Systematic Review concluded that, based on available data, H1-receptor antagonists cannot be recommended for the treatment of acute or chronic cough in children (Chang et al, 2008). The fairly common usage of H 1 -antihistamines for the treatment of cough in adults, albeit based on decades of clinical experience, overall is not supported by adequately performed clinical trials clearly demonstrating their effectiveness.…”
Section: Drugs In Current Use For the Treatment Of Coughmentioning
confidence: 99%
“…Quanto aos anti-histamínicos, de acordo com estudos randomizados, há um estudo favorável a cetirizina. 47 A observação por Otorrinolaringologia, para eventual avaliação de indicação cirúrgica, é igualmente útil.…”
Section: Tratamento Da Tosse Crónicaunclassified
“…Algumas revisões sistemáticas têm demonstrado que alguns desses medicamentos não apresentam benefício significativamente superior ao placebo no tratamento de síndromes das infecções de vias áreas superiores, como congestão nasal e rinorreia [40,41], tosse crônica inespecífica [42] e sinusite aguda [43]. Tais dados retratam a cultura regional de prevenir e tratar quadros de dor e febre, os quais muitas vezes podem ser contornados com medidas não medicamentosas [44].…”
Section: Artigo Originalunclassified