Anti-Hu antibodies, sensory neuropathy, and Holmes–Adie syndrome in a patient with seminoma

Müller, Niklas; Prass, Konstantin; Zschenderlein, Rolf

doi:10.1212/01.wnl.0000148709.28743.e7

Cited by 20 publications

(6 citation statements)

References 8 publications

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“…Other paraneoplastic neurological syndromes are infrequent and they are not associated with onconeural antibodies, except for a few exceptions [8]. PCD and germinoma were previously reported in three patients and the tumor antedated the diagnosis of PCD in all of them [3,9,10].…”

Section: Discussionmentioning

confidence: 94%

Paraneoplastic cerebellar degeneration associated with thymic germinoma

Solà-Valls¹,

Gaba²,

Muñoz³

et al. 2012

Journal of the Neurological Sciences

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Section: Discussionmentioning

confidence: 94%

Paraneoplastic cerebellar degeneration associated with thymic germinoma

Solà-Valls¹,

Gaba²,

Muñoz³

et al. 2012

Journal of the Neurological Sciences

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“…Histological studies showed loss of ganglion cells in the parasympathetic ciliary ganglia, which resulted in supersensitivity of the iris sphincter muscle (2). Mostly, Adie's pupil runs a benign clinical course, but occasionally is related with paraneoplastic syndrome (3). Here, we report a woman complaining of the weakness of lower extremities.…”

Section: Introductionmentioning

confidence: 99%

Anti-Hu Antibody-Associated Adie's Pupil and Paraneoplastic Sensorimotor Polyneuropathy Caused by Primary Mediastinal Small Cell Carcinoma

et al. 2019

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We report a woman with unilateral Adie's pupil associated with peripheral sensorimotor polyneuropathy, elevated anti-Hu antibody, and primary mediastinal small cell carcinoma (SCC). To our knowledge, this is the first report of Adie's pupil in a patient with mediastinal SCC. Although rare, Adie's pupil and sensorimotor polyneuropathy may be the first manifestation of cancer. Its rapid recognition facilitates an early diagnosis and treatment.

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“…1 Diseases such as giant cell arteritis, Sjogren's syndrome, malignancies, paraneoplastic anti-hu antibody syndrome and infections have been reported to be associated with tonic pupil. [2][3][4] There are few reports on occurrence of Adie's pupil during a migraine attack 1, 5-7 . Here we described a patient with a history of migraine who develops Adie's pupil during one of her attacks.…”

Section: Introductionmentioning

confidence: 99%

Adie’s Pupil During Migraine Attack: A Case Report

Chakma¹,

Datta²,

Datta³

et al. 2014

jemds

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Association of migraine and tonic pupil has been reported very rarely. We reported a young female with symptoms of migraine who developed a mydriatic pupil in one of her attacks. The pupil was unresponsive to light with little response to near reflex. In 0.125% pilocarpine test affected pupil responded significantly and tonic pupil was diagnosed. We discussed possible mechanisms and reviewed previous cases with the same diagnosis. Evidences show that this association may be caused by infarction of parasympathetic fibers secondary to prolonged vasospasm which sometimes occurs in migraine.

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Anti-Hu antibodies, sensory neuropathy, and Holmes–Adie syndrome in a patient with seminoma

Cited by 20 publications

References 8 publications

Paraneoplastic cerebellar degeneration associated with thymic germinoma

Paraneoplastic cerebellar degeneration associated with thymic germinoma

Anti-Hu Antibody-Associated Adie's Pupil and Paraneoplastic Sensorimotor Polyneuropathy Caused by Primary Mediastinal Small Cell Carcinoma

Adie’s Pupil During Migraine Attack: A Case Report

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