Anti-hyperglycemic and anti-hyperlipidemic effect of spices (Thymus vulgaris, Murraya koenigii, Ocimum gratissimum and Piper guineense) in alloxan-induced diabetic rats

Ekoh, Solomon Nwanze; Akubugwo, E. I.; Ude, Victor Chibueze; Edwin, N.

doi:10.12692/ijb/4.2.179-187

Cited by 16 publications

(6 citation statements)

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“…skorpilii var. skorpilii and T. vulgaris also exhibited antidiabetic activity in experimental diabetic rats and T. capitatus showed α-amylase inhibitory activity [16,[20][21][22][23][24].…”

Section: Discussionmentioning

confidence: 98%

Evaluation of enzyme inhibitory and antioxidant activity of some Lamiaceae plants

Ekin¹,

Orhan²,

Orhan³

et al. 2019

jrp

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Lamiaceae is one of the most widespread families in Turkey. The aim of this study was to determine antialzheimer, antidiabetic, antioxidant and antiobesity activities of ethanol extracts of Lamium purpureum var. purpureum, Origanum onites, Salvia sclarea, S. virgata and Thymus zygioides var. lycaonius. Acetylcholinesterase, butyrylcholinesterase, α-amylase, α-glucosidase, and pancreatic lipase inhibitory activities were tested for the determination of the activity of these extracts. Furthermore, total antioxidant, ferric-reducing antioxidant power, metalchelating and N,N-dimethyl-p-phenylendiamine radical scavenging assays were utilized to screen antioxidant activity. Total phenolic content of the extracts were also calculated. Among the tested extracts, T. zygioides var. lycaonius aerial part extract (85.28 ± 0.89 %) showed the highest inhibitory activity against α-glucosidase. The inhibitory activities of all extracts against α-amylase were lower than 50 %. S. sclarea leaf extract indicated remarkable butyrylcholinesterase inhibition (51.76 ± 1.04 %), but all of the plant extracts were inactive against acetylcholinesterase. The Salvia species showed the highest total antioxidant activity. S. sclarea flower (1.34 ± 0.08) and leaf (1.34 ± 0.08) extracts showed the highest ferric-reducing antioxidant power activities. Our findings indicated that O. onites, S. sclarea, S. virgata, and T. zygioides var. lycaonius extracts showed valuable inhibitory activity and emerged as the sources of possible α-glucosidase inhibitors for future studies.

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Section: Discussionmentioning

confidence: 98%

Evaluation of enzyme inhibitory and antioxidant activity of some Lamiaceae plants

Ekin¹,

Orhan²,

Orhan³

et al. 2019

jrp

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“…Thymus vulgaris is used worldwide as an infusion to treat respiratory ailments such as colds, congestion, sore throat, and both upper and lower respiratory infections, diabetes, and intestinal infections and infestations. It also has been described to have antiseptic, antibacterial, and antifungal properties (Ekoh et al, 2014;Prasanth Reddy et al, 2014). However, to date Thymus has not been investigated with respect to microbial communities.…”

Section: Introductionmentioning

confidence: 99%

Beneficial Endophytic Bacterial Populations Associated With Medicinal Plant Thymus vulgaris Alleviate Salt Stress and Confer Resistance to Fusarium oxysporum

Mohamad

Liu

et al. 2020

Front. Plant Sci.

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of cell-free extracts of B. subtilis (EGY16) showed at least ten compounds were known to have antimicrobial activity, with the major peaks being benzene, 1,3-dimethyl-, p-xylene, dibutyl phthalate, bis (2-ethylhexyl) phthalate, and tetracosane. This study demonstrates that diverse endophytes grow in wild thyme populations and that some are able to alleviate salinity stress and inhibit F. oxysporum pathogenesis, making them promising candidates for biofertilizers and biocontrol agents.

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“…For this reason, the natural products similar to the EOS may be suitable compounds to lunch control program against Varroa infestation and Nosema infection (Damiani et al 2009). Thyme (Thymus vulgaris) has anti-fungal, anti-bacterial, anthelmintic, antioxidant, and disinfectant effects and used as a syrup for digestive disorders and sore throat (Ekoh et al 2014). Lavender (Lavandula angustifolia) has also analgesic, antispasmodic, relaxing, antibacterial and antiparasitic effects (Dadman et al 2007;Denner 2009).…”

Section: )mentioning

confidence: 99%

The effects of plants extracts of thyme (Thymus vulgaris) and lavender (Lavandula angustifolia) on Varroa destractor (Acarina: Varroidae) and Nosema ceranae (Dissociodihaplophasida: Nosematidae) in adult worker honey bees (Apis mellifera)

Sarhangzadeh,

Yakhchali,

Moradi

2024

Preprint

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Varroa destructor is one of the important mites of the Western honey bees in Iran and throughout the world. Nosema ceranae is also cause of decreasing honey bee colony population. Herbal extracts are applicable replacement for chemical compounds in order to control bee mites and microsporidian agents. The aim of this study was to determine effects of hydro-alcoholic extracts of thyme and lavender in infected adult worker bees with V. destructor and N. ceranae. Hydro-alcoholic extracts and doses consisting of 2% thyme (2g/100ml) and 2% lavender (2g/100ml) were prepared and employed in treatment groups with three replicates. Dead mites were collected at 12, 24, 36, 48, and 72 hours and efficacy was measured. Twenty examined adult bees were collected at 24, 36, 48, and 72 hours and spores’ reduction were determined. The highest mortality effects of plant extracts of thyme and lavender on V. destructor was 81% and 76% at 48h, respectively. The extracts had significant association with mortality of V. destructor and their efficacies were comparable to Apistan. Decreasing of number of N. ceranae spores was significant in comparing with each plant extracts and their efficacies were comparable to fumagilin. Nosema spores' reduction in bees was 4–5 fold less after extract treatment. The plant extract of thyme had higher antimicrosporidian activity against N. ceranae than lavender and inhibited the development of Nosema spores after 72h of treatment. It is concluded that the extract plants might be applicable alternative compounds in V. destructor and N. ceranae control in bees' colonies.

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Anti-hyperglycemic and anti-hyperlipidemic effect of spices (Thymus vulgaris, Murraya koenigii, Ocimum gratissimum and Piper guineense) in alloxan-induced diabetic rats

Cited by 16 publications

References 0 publications

Evaluation of enzyme inhibitory and antioxidant activity of some Lamiaceae plants

Evaluation of enzyme inhibitory and antioxidant activity of some Lamiaceae plants

Beneficial Endophytic Bacterial Populations Associated With Medicinal Plant Thymus vulgaris Alleviate Salt Stress and Confer Resistance to Fusarium oxysporum

The effects of plants extracts of thyme (Thymus vulgaris) and lavender (Lavandula angustifolia) on Varroa destractor (Acarina: Varroidae) and Nosema ceranae (Dissociodihaplophasida: Nosematidae) in adult worker honey bees (Apis mellifera)

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