Anti-hyperglycemic effect of herbal formula of Moringa oleifera, Vernonia amygdalina and Centella asiatica extracts in streptozotocin-induced hyperglycemic mice

Tran, Thi Thanh Loan; Ly, Hai Trieu; Le, Thi Kim Oanh; Le, Van Minh

doi:10.1016/j.prmcm.2024.100428

Pharmacological Research - Modern Chinese Medicine

2024

DOI: 10.1016/j.prmcm.2024.100428

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Anti-hyperglycemic effect of herbal formula of Moringa oleifera, Vernonia amygdalina and Centella asiatica extracts in streptozotocin-induced hyperglycemic mice

Thi Thanh Loan Tran,

Hai Trieu Ly,

Thi Kim Oanh Le

et al.

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2024

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Centella asiatica and its bioactive compounds: a comprehensive approach to managing hyperglycemia and associated disorders

Singh,

Singh

2024

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Centella asiatica (CA), (also known as Centella asiatica (L.) Urb. or Indian pennywort or Gotu Kola) is native to the tropical regions of Asia and Africa and has a rich history of use in treating a wide range of ailments, including neurological, dermatological, immunological, and metabolic disorders. This plant is rich in bioactive compounds, such as pentacyclic triterpenes (notably Asiaticoside, Asiatic Acid, Madecassoside, and Madecassic Acid), flavonoids, phytosterols, and phenolic acids, which contribute significantly to its therapeutic effectiveness. The medicinal applications of CA are vast, with its chemical constituents exhibiting notable therapeutic potential in areas such as antidiabetic, antimicrobial, anti-inflammatory, anticancer, neuroprotective, antioxidant, and wound healing activities. Numerous scientific investigations have validated these applications, confirming the efficacy of its bioactive components. In this critical review, we have conducted a comprehensive analysis of the existing literature to shed light on the pharmacological significance of CA, particularly concerning diabetes and related disorders.

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Centella asiatica and its bioactive compounds: a comprehensive approach to managing hyperglycemia and associated disorders

Singh,

Singh

2024

Discov. Plants

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Anti-hyperglycemic effect of herbal formula of Moringa oleifera, Vernonia amygdalina and Centella asiatica extracts in streptozotocin-induced hyperglycemic mice

Cited by 1 publication

References 64 publications

Centella asiatica and its bioactive compounds: a comprehensive approach to managing hyperglycemia and associated disorders

Centella asiatica and its bioactive compounds: a comprehensive approach to managing hyperglycemia and associated disorders

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