Anti-hyperlipidemic effects of Campomanesia xanthocarpa aqueous extract and its modulation on oxidative stress and genomic instability in Wistar rats

Walnut Seed Coat (Juglans regia L.), a Plant Effective in Human Health: Antioxidant Activity and in Rats Nephroprotective Effect

“…A model of acute hyperlipidemia was created in rats within 24 hours with Triton WR-1339, which we used in our current study. Our model was supported by using this induction in the study in which the anti-hyperlipidemic properties of Campomanesia xanthocarpa leaves (De Sousa et al, 2019) and N-(Benzoylphenyl)-Carboxamide derivatives were determined (Sweidan et al, 2022). With the application of Triton WR-1339 by Attia et al (2020), TGs, TC, LDL-C and lipid peroxidation (LPO) increased and HDL-C decreased (Attia et al, 2020).…”

Mechanistic considerations and biomarkers level in nickel-induced neurodegenerative diseases: An updated systematic review

“…Administration of NiCl 2 male Wistar rats resulted in an increase in the reduced glutathione content (GSH), glutathione-S-transferase (GST), glutathione reductase (GR), LPO, H 2 O 2 generation, with a concomitant decrease in the activity of glutathione peroxidase (GPx) ( Prasad et al, 2006 ). Several studies reported oxidative damage in brain of rats exposed to nickel with significantly induced increase of LPO, and reduction of GSH level as well as the decrease of superoxide dismutase (SOD) and catalase (CAT) activities ( Ijomone et al, 2020a , Wang et al, 2020 , De Sousa et al, 2019 , Deniz and Altun, 2020 ). In treated male Wistar albino rats, nitric oxide (NO) and LPO levels in whole brain tissue and plasma increased following nickel sulfate (NiSO 4 , 6 H 2 O) treatment ( Ridnour et al, 2004 , Das and Saha, 2010 ).…”

Evaluation of nickel-induced brain injuries in rats via oxidative stress and apoptosis: attenuating effects of hyperoside

“…The most commonly used indicators of lipid peroxidation are TBARS products (De Sousa, 2019). Therefore, TBARS levels were measured in the rat brain to evaluate the Ni-induced lipoperoxidation and modulation by Hyp.…”