Anti-<i>Helicobactor pylori</i> activity of some Jordanian medicinal plants

Masadeh, Majed M; Alkofahi, Ahmad S.; Alzoubi, Karem H.; Tumah, Haitham; Bani-Hani, Kamal E.

doi:10.3109/13880209.2013.853811

Cited by 36 publications

(25 citation statements)

References 18 publications

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“…Hypoglycemic properties via stimulation of glucose uptake Afifi-Yazar et al 2011;Talib et al 2012;Seca et al 2014). Antimicrobial and anti-Helicobacter pylori efficacies (Karygianni et al 2014;Masadeh et al 2014). …”

Section: Introductionmentioning

confidence: 99%

The use of medicinal herbs in gynecological and pregnancy-related disorders by Jordanian women: a review of folkloric practice vs. evidence-based pharmacology

Akour

Kasabri

Afifi

et al. 2016

Pharmaceutical Biology

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Context National statistical reports in Jordan indicate a decrease in the total fertility rate along with a parallel increase in contraceptive use. The folkloric use of medicinal herbs in gynecological disorders has been growing in Jordan, despite of deficient reports on the evidence-based safety and efficacy of these practices. Objective The aim of this comprehensive article is to review medicinal plants with claimed ethnonpharmacological usage in various gynecological and pregnancy-related issues in Jordan, and to assess their evidence-based pharmacological studies as well as their phytochemistry. Methods The published literature was surveyed using Google Scholar entering the terms ''ethnopharmacology AND Jordan AND infertility AND gynecology OR gestation''. We included ethnopharmacological surveys in Jordan with available full-text. Results Twelve articles were reviewed. Plant species which are commonly used for female gynecological issues such as Artemisia monosperma Del. and A. herba-alba Asso. (Asteraceae) have been found to exert an antifertility effect. Ricinus communis L. (Euphorbiaceae) and Citrullus colocynthis (L.) Schrad. (Cucurbitaceae) had antifertility effects in male rats, but Nigella sativa oil L. (Ranunculaceae) and Cinnamon zeylanicum J. Presl (Lauraceae) were found to enhance it. Conclusion Using plants for gynecological disorders is a common practice in Jordan. Many of them, whether utilised for gynecological or non-gynecological conditions equally, were found to have detrimental effects on female or male fertility. Thus, couples planning pregnancy should be discouraged from the consumption of these herbs. Further local studies are warranted to confirm the appreciable beneficial pharmacological effects and safety of these plants. ARTICLE HISTORY

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Section: Introductionmentioning

confidence: 99%

The use of medicinal herbs in gynecological and pregnancy-related disorders by Jordanian women: a review of folkloric practice vs. evidence-based pharmacology

Akour

Kasabri

Afifi

et al. 2016

Pharmaceutical Biology

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“…On the other hand the petroleum ether and hexanic extracts of C. spinosa aerial parts showed a similar activity of inhibition against both gram-positive and gram-negative bacterial species tested such as Helicobacter pylori, Escherichia coli and Bacillus cereus [30,31].…”

Section: Antimicrobial Acivitymentioning

confidence: 77%

Pharmacological Properties of Capparis spinosa Linn

A¹,

Farid²,

Eddouks³

2015

IJDVR

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“…Anethum graveolens ethanolic fraction affecting Helicobacter pylori one of stomach ulcer-causative agents,[ 20 ] the essential oil of Shbint was active in vitro against several Candida with MIC of 0.3–0.6 μL/mL. [ 21 ] The methanolic extract of the leaves showed weak to moderate antibacterial activities with MIC of 5000 μg/mL against Escherichia coli and 2500 μg/mL against Pseudomonas aeruginosa and Staphylococcus aureus ,[ 22 ] which come in accordance with our results on the other hand, the extraction of A. graveolens by MeOH leading to the production of moderate antibacterial fraction with MIC of 1250 μg/mL against E. coli and S. aureus and 5000 μg/mL against P. aeruginosa .…”

Section: Discussionmentioning

confidence: 99%

Screening of fruits of seven plants indicated for medicinal use in Iraq

Aldulaimi

2017

Phcog Mag

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Introduction:Coumarins exert many biological effects in humans, animals, and plants, which make the evaluation of their biological activities and study of their role in ethnomedicine highly valued.Objectives:Here, we selected seven plants which have ethnopharmacological use as antimicrobial in Iraq and the aims were to quantify the two structural isomers bergapten and methoxsalen in their seeds, to evaluate the antibacterial activities against several clinical isolates, and to isolate bergapten and methoxsalen from Ammi majus.Materials and Methods:Seven plants were extracted by petroleum ether (PE) and ethanol (EtOH). Bergapten and methoxsalen were separated and purified by preparative thin-layer chromatography. Quantification of the furanocoumarins has been conducted by high-performance liquid chromatography, and all the plant extracts and pure compounds were checked for antibacterial activities utilizing alamar blue microplate assay.Results:Cuminum cyminum was deprived of bergapten and methoxsalen and methoxsalen was not detected from Apium graveolens. Bergapten was abundant in PE more than in EtOH; on the other hand, EtOH was rich in methoxsalen. The separation of the two structural isomers was performed using normal phase chromatography and ultraviolet light as an indicator. All extracts showed weak to moderate antibacterial activities against Gram-positive isolates which were more sensitive than the negative ones. C. cyminum extract was least active, uncover the antibacterial role of bergapten and methoxsalen.Conclusion:These findings support the medicinal use of seeds of seven plants from Apiaceae family and quantify the two pharmacologically important furanocoumarins (bergapten and methoxsalen).SUMMARY This study was conducted to evaluate the antibacterial activities of seven plants seeds used in local medicine in Iraq. High-performance liquid chromatography was used to quantify bergapten and xanthotoxin in non-polar and polar extracts of these seeds. This study supports the medicinal use of these plants and clarifies the role of bergapten and xanthotoxin in antibacterial activities of these plants. Abbreviations used: EtOH: Ethanol; MIC: Minimum inhibitory concentration; PE: Petroleum ether; Rf: Retardation factor; Rt: Retention time.

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Anti-Helicobactor pylori activity of some Jordanian medicinal plants

Cited by 36 publications

References 18 publications

The use of medicinal herbs in gynecological and pregnancy-related disorders by Jordanian women: a review of folkloric practice vs. evidence-based pharmacology

The use of medicinal herbs in gynecological and pregnancy-related disorders by Jordanian women: a review of folkloric practice vs. evidence-based pharmacology

Pharmacological Properties of Capparis spinosa Linn

Screening of fruits of seven plants indicated for medicinal use in Iraq

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