Anti-Idiotypic Monoclonal Antibodies Against Morphine: Production, Properties and Prospects of Use

Abstract

This paper describes a technique for producing anti-idiotypic monoclonal antibodies (Ab2) against two morphine derivatives. The specificity of the obtained antibodies was investigated using enzyme immunoassay. The biological activity of the antibodies was studied using an in-vitro model of human glioblastoma T98G cell line prolifer ation.