Anti-inflammatory activity of Myristica fragrans extract

Abstract

In simple terms, in lammation can be de ined as a reaction from the body to an injury in living tissue. Anti-in lammatory drugs help in controlling and reducing this in lammation. Natural spice showing anti-in lammatory properties with no side effects, hence they can be used as an ef icient anti-in lammatory drug in the near future. To determine the anti-in lammatory activity of Myristica fragrans (Nutmeg) using MTT Assay. The plant material was obtained as a gift sample from Life Care Phytolabs Private Limited. An extract was prepared from the sample. Cell viability assay -MTT Assay was performed, and Raw cell line 247 was used to study the anti-in lammatory potential of the extract. The results collected were put into a graph and table for discussion. A gradual decrease in the number of in lammatory cells as the concentration of the extract was increased was observed in the in lammatory cell line. The cell viability, which was 7.08% when the concentration of the extract was 1ng increased up to 30.6% when the concentration of the extract was increased up to 100ug. The MTT assay test on a raw cell line 247 showed that the Myristica fragrans extract exhibits some level of the anti-in lammatory property. Further research on isolating the speci ic component of the extract responsible for its anti-in lammatory property can be done in the future.

Anti-inflammatory activity of lauric acid, thiocolchicoside and thiocolchicoside-lauric acid formulation

“…Phytochemical constituents from plants are extracted using polar and nonpolar solvents [ 6 ; 7 ]. Some studies revealed that the medicinal property of plant extracts is mainly dependent on the dosage of extract and solvent used for extraction [ 8 ; 9 ]. Nowadays, natural products are found safer than synthetic medications, which are viewed as harmful.…”