Anti-inflammatory Activity of Pectolinarigenin and Pectolinarin Isolated from Cirsium chanroenicum

Lim, Hyun; Son, Kun Ho; Chang, Hyeun Wook; Bae, KiHwan; Kang, Sam Sik; Kim, Hyun Pyo

doi:10.1248/bpb.31.2063

Cited by 110 publications

(68 citation statements)

References 31 publications

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“…1) by the spectroscopic data and comparison with a previous report in the literature (Simoes et al 2013). Pectolinarin (1) has shown significant anti-inflammatory activity in various in vivo models as well as anti-allergic and analgesic properties (Martinez-Vazquez et al 1998;Lim et al 2008). Therefore, large amounts of pectolinarin (1) may have some potential uses in natural medicinal products, health supplements, and beverages.…”

Section: Resultsmentioning

confidence: 93%

“…Cirsium spp. is also bioactive and has antimicrobial, anti-diabetic, anti-oxidant, hepatoprotective, antiinflammatory, vasorelaxant, and anti-cancer properties (Perez et al 2001;Park et al 2004;Nazaruk and Jakoniuk 2005;Liu et al 2007;Jeong et al 2008;Kim et al 2008;Ku et al 2008;Lim et al 2008;Yoo et al 2008).…”

Section: Introductionmentioning

confidence: 99%

“…Pectolinarin has anti-tumor, hepatoprotective, and anti-inflammatory activities (Lim et al 2008;Yoo et al 2008). However, there have been few quantitative studies of pectolinarin in Cirsium spp.…”

Section: Introductionmentioning

confidence: 99%

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Determination of pectolinarin inCirsiumspp. using HPLC/UV analysis

Cho

Lee

et al. 2016

JABC

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Pectolinarin was isolated from the ethyl acetate fraction of Cirsium setidens using open column chromatography and was analyzed using spectrometry. Pectolinarin content in Cirsium spp. was determined using HPLC/UV. Pectolinarin content in the aerial part of Cirsium spp. was higher than that in the root and pappus. Pectolinarin content was highest in the aerial part of C. chlorolepis (110.65 mg/g extract). Consequently, the aerial part of C. chlorolepis has potential for use in new natural medicinal products, health supplements, and beverages.

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Section: Resultsmentioning

confidence: 93%

Section: Introductionmentioning

confidence: 99%

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Determination of pectolinarin inCirsiumspp. using HPLC/UV analysis

Cho

Lee

et al. 2016

JABC

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“…All of these results suggest that pectolinarigenin and pectolinarin possess anti-inflammatory activity and that they may inhibit eicosanoid formation in inflammatory lesions. These activities certainly contribute to the anti-inflammatory effects of C. chanroenicum (Lim et al 2008).…”

Section: Leandro R Simões Et Almentioning

confidence: 99%

Chemical constituents of Distictella elongata (Vahl) Urb. (Bignoniaceae)

Simoes

Maciel

Brandão

et al. 2013

An. Acad. Bras. Ciênc.

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Pectolinarin, a flavone heteroside, was isolated from Distictella elongata (Vahl) Urb. leaves ethanol extract, along with a mixture of ursolic, pomolic and oleanolic acids, besides β-sitosterol. Their structures were established on the basis of spectral analysis ( 1 H and 13 C NMR, 1 D and 2 D) and they were compared with literature. This is the first report on the occurrence of this flavonoid in a species of the Bignoniaceae family.

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“…Cannabis sativa (Cannabaceae) Mimosa pudica (Mimosoideae) Anti oxidant [85] 34 Oroxylin Oroxylum indicum (Bignoniaceaea) Apoptosis [86] www.wjpps.com [87] 36 Pongamol Tephrosia purpurea (Fabaceae) antihyperglycemic [88] 37 Prunetine Butea monosperma (Fabaceae) Anti oxidant [89] 38 Purpurin Tephrosia purpurea (Fabaceae) Antifungal [90] 39 Pinocembrin Nicrembergia hippomania (Solanaceae) Anti-feedant [91] 40 Peonidin Vitis vinifera (Vitaceae) Antioxidant [92] www.wjpps.com Antioxidant, Anticancer [93] 42 Petunidin Solanum tuberosum (Solanaceae) Antioxidant [94] [97] 45 Tambuletin Zanthoxylum alatum (Rutaceae) Antioxidant [98] www.wjpps.com Anti-inflammatory, Antioxidant [69] 49 Vitexin Passiflora incarnate (Passifloraceae) Antioxidant , Antithyroid [100] 50 Vitexicarpin Vitex rotundifolia (Lamiaceae) Antiproliferative [82] www.wjpps.com Vol 6, Issue 5, 2017. 500…”

Section: Chemistry Of Flavonoidsmentioning

confidence: 99%