ANTI-INFLAMMATORY AND ANALGESIC ACTIVITIES OF AVOCADO SEED (Persea americana Mill.)

Abstract

The purpose of this research is to evaluate the anti-inflammatory and analgesic activities of infusion and methanolic extract from avocado seeds. The anti-inflammatory activity was

Anti-inflammatory effects of avocado peels against inflammation induced by carrageenan in mice

“…The results obtained in the rat paw edema show that the active principles present in the avocado peel may act analogously in the inflammatory response produced by carrageenan. These results are similar with a previous report in which the same doses of avocado seed infusion and extract had antiinflammatory activities (Kristanti et al, 2017). Avocado leaves also possess anti-inflammatory activity (Adeyemi et al, 2002).…”

“…Group II, as negative control group for avocado peel extract, were given CMC-Na, and group III, as positive control, were given Cataflam Fast® (Pottasium Diclofenac) 4.48 mg /kgBW. Groups IV -VI were given avocado peel infusion with 3 levels of doses, 667.5; 1335; and 2670 mg/kgBW (Kristanti et al, 2017). Groups VII -IX were given avocado peel decoction with 3 levels of doses which were 667.5; 1335; and 2670 Pharmaciana ISSN: 2088 4559; e-ISSN: 2477 0256…”

“…221 mg/kgBW. Groups X -XII were given avocado peel extract with 3 levels of doses which were 830; 1670; and 3330 mg/kgBW (Kristanti et al, 2017).…”

“…Edema thickness in mice's paw was measured using digital caliper at 0, 15,30,45,60,90,120,150,180,210,240,270,300,330, and 360 minutes after carrageenan injection (Tjandrawinata et al, 2015;Hendra et al, 2017;Kristanti et al, 2017) using the equation as followed:…”

A Review on Avocado Seed: Functionality, Composition, Antioxidant and Antimicrobial Properties

“…According to the study of Daihan et al [42], avocado seed used in traditional medicine for the treatment of various ailments and has antibacterial, antifungal, anti-viral and woundhealing properties. They reported that, antioxidant potential of plant extracts was evaluated by means of total phenolic, total flavonoids content and DPPH radical scavenging activity.…”