Anti-inflammatory and antinociceptive features of Bryonia alba L.: As a possible alternative in treating rheumatism

İlhan, Mert; Dereli, Fatma Tuğçe Gürağaç; Tümen, İbrahim; Akkol, Esra Küpeli

doi:10.1515/chem-2019-0003

Cited by 11 publications

(10 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Separate assays have been done on B. alba , sometimes in combination with B. dioica [100–102]. Moreover, B. alba roots have high phenolic and flavonoid content [103]. The recognised pharmacologically medicinal activities of B. alba are anti-rheumatic, expectorant and anti-inflammatory [103].…”

Section: Resultsmentioning

confidence: 99%

“…Moreover, B. alba roots have high phenolic and flavonoid content [103]. The recognised pharmacologically medicinal activities of B. alba are anti-rheumatic, expectorant and anti-inflammatory [103]. Although, historical and some folk medicinal sources have mentioned B. alba as a remedy for epilepsy, there are not enough studies to confirm its application in epilepsy [104].…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

From medicinal plant to noxious weed: Bryonia alba L. (Cucurbitaceae) in northern and eastern Europe

Kujawska

Svanberg

2019

J Ethnobiology Ethnomedicine

View full text Add to dashboard Cite

Introduction White bryony, Bryonia alba L., is a relatively little known plant in the history of folk medicine and folk botany in eastern and northern Europe. The main aim of this article is to bring together data about Bryonia alba and to summarise its cultural history and folk botanical importance in eastern and northern Europe. Nowadays, this species is considered at best as an ornamental plant, and at worst as a noxious weed. However, ethnographic and historical sources show that it used to be of magical, medicinal and ritual importance in our part of Europe. Methods A diachronic perspective was chosen in order to outline and analyse the devolution and changes in the use of B. alba , in the course of which we take into account the social, ecological and chemical aspects of the usage of this plant. We have therefore traced down and analysed published sources such as ethnographical descriptions, floras, linguistic records and topographical descriptions from northern and central-eastern Europe, particularly Scandinavia, Baltic States, Germany, Poland, Belarus, Ukraine and the Balkan Peninsula. The analysed material is presented and discussed within the biocultural domains that developed in the interaction between human societies and Bryonia alba . Results and discussion Bryonia alba has many folk names in northern and central-eastern parts of Europe: some of them refer to its medicinal properties, life form, odour, or toxicity; others to its possession by the devil. As we learn, Bryonia alba was an inexpensive surrogate for mandrake ( Mandragora officinarum L.) and sold as such in the discussed parts of Europe. The folklore and medicinal properties ascribed to mandrake were passed on to white bryony due to an apparent resemblance of the roots. In ethnographic descriptions, we find a mixture of booklore, i.e. written traditions, and oral traditions concerning this species. Some of this folklore must have been an alternative stories spread by swindlers who wished to sell fake mandrake roots to people. Conclusions Plant monographs and reviews of particular species tend to concentrate on the botanicals, which might have great useful potential. White bryony presents a precisely opposite example, being a plant that used to be of medicinal relevance and was furnished with symbolical meaning, and has nowadays preserved only its ornamental value among some urban and rural dwellers of northern Europe. Nonetheless, it might be considered as a part of the biocultural heritage in old, well-preserved gardens. It is still used as a medicine in some parts of the Balkan Peninsula.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

From medicinal plant to noxious weed: Bryonia alba L. (Cucurbitaceae) in northern and eastern Europe

Kujawska

Svanberg

2019

J Ethnobiology Ethnomedicine

View full text Add to dashboard Cite

show abstract

“…Cucurbitaceae methanolic Root Anti-inflammatory and antinociceptive Mert Ilhan et al . [89] Juniperus sabina L Cupressaceae Ethanolic extract…”

Section: Dragos Paulmentioning

confidence: 99%

Comprehensive Review on Hemorrhoids: From Epidemiology to Preclinical Assessment of Anti-Hemorrhoidal Agents

Bairagi,

Kulkarni,

Gunjal

et al. 2024

Int. J. Pharm. Sci. Drug Res.

View full text Add to dashboard Cite

The review discusses the etiology, epidemiology, classification, risk factors, assessment, the role of biomarkers in the development of hemorrhoids, Operative, and Non-operative treatment options, postoperative complications of hemorrhoids, preclinical evaluation methods of anti-hemorrhoidal drugs, and different medicinal plants that show anti-hemorrhoidal activity. Hemorrhoids are characterized by the expansion and dislocation of typical anal cushions. One of the most significant discoveries regarding hemorrhoids is the atypical vascular channel dilatation and distortion, along with damage and modifications to the anal cavity's supporting connective tissue. Based on different factors, hemorrhoids are categorized in different classifications out of which Golingher’s classification is commonly used which divides the hemorrhoidal condition into 4 grades according to prolapse and development of hemorrhoids. Hemorrhoids are recognized as one of the main causes of morbidity which affects millions of people worldwide and also increases the economic overload on the health care system. Using current treatment options hemorrhoids are often treated conservatively using a variety of techniques, including fiber supplements, anti-inflammatory medications, lifestyle changes, and venotonic medicines. As well as using operative treatments like rubber band ligation, hemorrhoidectomy, and Injection sclerotherapy also various biomarkers play an important role in the progression of hemorrhoids like Matrix Metalloproteinase (MMP), inducible nitric oxide synthase (iNOS), and C-reactive protein (CRP), and Vascular endothelial growth factor (VEGF). These biomarkers can be a potential target for the development of new anti-hemorrhoidal agents.

show abstract

“…Відомо, що види бріонії мають такі біологічні дії, як знеболювальну, протизапальну, антиоксидантну, жарознижувальну, протимікробну, ларвіцидну й цитотоксичну. Екстракт, приготовлений з коренів Bryonia alba, виявляв статистично значущу протизапальну, антиноцицептивну й антиоксидантну активність, яку можна пояснити дією фенольних сполук і тритерпеноїдів типу куркурбітану [43].…”

Section: комплеêсниé гомеопатичниé препарат гомеовоêсunclassified

Эффективность И Безопасность Применения Гомеопатических Лекарственных Препаратов При Острых Респираторных Вирусных Инфекциях С Позиции Доказательной Медицины (Международный Опыт)

Moshchych¹,

Kramarov²

2021

View full text Add to dashboard Cite

В данной обзорной статье речь идет о необходимости понимания основы эффективности и безопасности применения гомеопатических лекарственных препаратов при острых респираторных вирусных инфекциях (ОРВИ) с позиции доказательной медицины. Гомеопатические лекарственные препараты рассмотрены с точки зрения составляющей наномедицины с учетом открытий, сделанных в течение последних десятилетий в этой области знаний, а также с учетом того, что течение ОРВИ в основном проявляется функциональными нарушениями. Отмечена целесообразность использования отдельных компонентов гомеопатических лекарственных средств именно в низких/гомеопатических/наноконцентрациях с учетом их дозозависимого профиля безопасности. В качестве примера проанализированы препараты французского происхождения — Оциллококцинум, Коризалия, Гомеовокс и Стодаль. За многие десятилетия практического использования указанных препаратов наработана достаточно весомая научная база, существует ряд статей, опубликованных в различных странах мира, подтверждающих их эффективность и безопасность. Рассмотрены не только клинические исследования относительно вышеупомянутых препаратов, но также освещены вопросы механизма их действия на основе фармакодинамических свойств отдельных компонентов. Указана необходимость рассматривать любой лекарственный препарат, в том числе гомеопатический, как с позиции доказательной медицины, так и в более широком смысле, с учетом современного подхода к здравоохранению на основе ценности. С учетом проанализированной информации сделан вывод, что вышеупомянутые препараты — Оциллококцинум, Коризалия, Гомеовокс, Стодаль — отвечают этим требованиям и должны быть более широко внедрены в клиническую практику.

show abstract

Anti-inflammatory and antinociceptive features of Bryonia alba L.: As a possible alternative in treating rheumatism

Cited by 11 publications

References 41 publications

From medicinal plant to noxious weed: Bryonia alba L. (Cucurbitaceae) in northern and eastern Europe

From medicinal plant to noxious weed: Bryonia alba L. (Cucurbitaceae) in northern and eastern Europe

Comprehensive Review on Hemorrhoids: From Epidemiology to Preclinical Assessment of Anti-Hemorrhoidal Agents

Contact Info

Product

Resources

About