Anti-microbial Activity of Korean Fermented Soybean Paste (Doen-jang) Against Oral Microbes

Lee, Seong Lim; 김종규,

doi:10.5668/jehs.2008.34.3.207

Cited by 8 publications

(6 citation statements)

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“…For example, the interaction of phytoestrogens with ER as well as their antioxidant properties might contribute to its neuroprotective effects (Gorzkiewicz et al, 2021). Several studies showed that different forms of soybean including soy isoflavones have antibacterial activity against oral microbes (Lee & Kim, 2006;Wang et al, 2010;Laodheerasiri and Horana Pathirage, 2017;Choo et al, 2020;How et al, 2020). Antimicrobial activity of phytoestrogens may be useful for the treatment and prevention of periodontal disease as periodontitis is known to have bacterial cause.…”

Section: Figurementioning

confidence: 99%

Overview on postmenopausal osteoporosis and periodontitis: The therapeutic potential of phytoestrogens against alveolar bone loss

et al. 2023

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Osteoporosis and periodontitis are two major chronic diseases of postmenopausal women. The association between these two diseases are evident through systemic bone loss and alveolar bone loss. Both postmenopausal osteoporosis and periodontitis impose a considerable personal and socioeconomic burden. Biphosphonate and hormone replacement therapy are effective in preventing bone loss in postmenopausal osteoporosis and periodontitis, but they are coupled with severe adverse effects. Phytoestrogens are plant-based estrogen-like compounds, which have been used for the treatment of menopause-related symptoms. In the last decades, numerous preclinical and clinical studies have been carried out to evaluate the therapeutic effects of phytoestrogens including bone health. The aim of this article is to give an overview of the bidirectional interrelationship between postmenopausal osteoporosis and periodontitis, summarize the skeletal effects of phytoestrogens and report the most studied phytoestrogens with promising alveolar bone protective effect in postmenopausal osteoporosis model, with and without experimental periodontitis. To date, there are limited studies on the effects of phytoestrogens on alveolar bone in postmenopausal osteoporosis. Phytoestrogens may have exerted their bone protective effect by inhibiting bone resorption and enhancing bone formation. With the reported findings on the protective effects of phytoestrogens on bone, well-designed trials are needed to better investigate their therapeutic effects. The compilation of outcomes presented in this review may provide an overview of the recent research findings in this field and direct further in vivo and clinical studies in the future.

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Section: Figurementioning

confidence: 99%

Overview on postmenopausal osteoporosis and periodontitis: The therapeutic potential of phytoestrogens against alveolar bone loss

et al. 2023

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“…구강은 입술, 혀, 잇몸, 구강 점막으로 이루어진 인체에 중 요한 기관으로 외부와 직접적으로 통하고 있어 환경적으로 세 균들이 증식하기 알맞은 조건을 가지고 있다 1) . Streptococcus mutans (S. mutans)는 충치 원인균으로 glucosyltransferase (GTase) 라는 효소를 분비하며 GTase가 음식물 중 자당을 분해함으로써 불용성 글루칸 (glucan)을 형성한다.…”

Section: 서 론 1)unclassified

Anti-microbial Effect on Streptococcus mutans and Anti-oxidant Effect of the Butanol Fractions of Sanguisorbae Radix

Park¹,

Lee²,

2012

The Korea Journal of Herbology

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Objective : Sanguisorbae Radix (SO). that belong to Rosaceae is widely distributed in Asia including Korea, Japan and China. It has been used as traditional medicine from old times as a treatment for anti-inflammatory drugs. This study was designed to investigate the effects of n-BuOH fractions of SO on anti-oxidant effect and anti-microbial effect on Streptococcus mutans (S. mutans). Methods : The anti-microbial effect of n-BuOH fractions of SO. was assessed by the paper disk diffusion method and anti-oxidant effect was assessed by the DPPH radical scavenging effect, Superoxide anion radical scavenging effect and SOD like ability.Results : DPPH radical scavenging of the n-BuOH fraction from SO in 50 ug/mL was shown to be Fr-2 (89.9%), Fr-3 (88.7%), Fr-4 (76.3%), Fr-1 (59.4%), Fr-5 (56.2%). Superoxside anion radical scavenging activity of the n-BuOH fraction from SO. in 50 ug/mL for Fr-3 was shown to be 78%. SOD-like activity of n-BuOH fraction from the SO in 1000 ug/mL for Fr-3 were shown to be 76.1% respectively. The n-BuOH fraction from the SO had high anti-microbial effect on S. mutans. Conclusion : As a result, the n-BuOH fraction from SO. has good anti-microbial and anti-oxidant effects in a concentration-dependent manner.

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“…The oral cavity is an important organ in the human body, exposed to many microorganisms because it communicates directly with the outside world and offers environmental conditions suitable for the growth of bacteria, resulting in various oral diseases [ 1 ]. Moreover, as the importance of oral health has increased, especially due to the rise in mask-wearing as a result of viral infections, interest in managing bacteria in the mouth has increased [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the Antifungal Effect of Rhus verniciflua Stokes Extract for Oral Application Potential

Kim,

Nam

2023

Medicina

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Background and Objectives: This study confirms the possibility of using Rhus verniciflua Stokes (RVS) extract as a natural treatment for oral candidiasis. Materials and Methods: RVS was extracted with 70% ethanol to examine the antioxidant activity through polyphenol, flavonoid content, and DPPH (1,1-diphenyl-2-picrylhydrazyl). To evaluate the antifungal effect against Candida albicans (C. albicans; KCTC 7965/ATCC 10231) and evaluate the stability of RVS, a water-soluble tetrazolium salt (WST-1) assay was performed in human keratinocytes (HaCaT). Results: The findings revealed that RVS extract has fairly high antioxidant activity. The clear zones of the RVS extract against C. albicans increased in diameter due to the inhibition of fungal growth at higher concentrations. Treatment with the 1.25 mg/mL RVS extract had a more than 99% antifungal effect against C. albicans, and the 20 mg/mL RVS extract had a 100% antifungal effect. The WST-1 assay showed that the RVS extract induced low cell viability in the HaCaT cells, which inhibited their proliferation, and the RVS extract is also toxic to normal cells. Conclusions: Although the RVS extract with high antioxidant activity showed clear antifungal activity against C. albicans, it exhibited a low survival rate. Therefore, the development of a safe natural antibiotic is necessary.

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Anti-microbial Activity of Korean Fermented Soybean Paste (Doen-jang) Against Oral Microbes

Cited by 8 publications

References 1 publication

Overview on postmenopausal osteoporosis and periodontitis: The therapeutic potential of phytoestrogens against alveolar bone loss

Overview on postmenopausal osteoporosis and periodontitis: The therapeutic potential of phytoestrogens against alveolar bone loss

Anti-microbial Effect on Streptococcus mutans and Anti-oxidant Effect of the Butanol Fractions of Sanguisorbae Radix

Evaluation of the Antifungal Effect of Rhus verniciflua Stokes Extract for Oral Application Potential

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