Anti-microbial efficacy of Allium sativum against Streptococcus mutans biofilm formation on orthodontic mini-implants

Khan, Lubna; Paulino, Even Grace Miranda; Lim, Dennis; Nadela, Federico; Yadav, R. N.; Birring, Ourvind Jeet Singh

doi:10.4103/2321-3825.140683

Cited by 12 publications

(11 citation statements)

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“…In this study, garlic extract was diluted to a concentration of 64 mg/ml in accordance with a study by Khan L et al ., as this concentration was most potent as an antimicrobial. [ 4 ] At room temperature, the extract can be stored for maximum 7 days, while at −20°C temperature, it can be stored for 90 days. [ 16 ]…”

Section: Discussionmentioning

confidence: 99%

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A scanning electron microscope evaluation of efficacy of sodium hypochlorite and Allium sativum in smear layer removal in root canals with the use of modified evacuation system: An ex vivo study

Prabhakaran

Mariswamy

2018

J Conserv Dent

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Context:Sodium hypochlorite (NaOCl) is the most widely used endodontic irrigant. Although it fulfills most of the requisites of an ideal irrigant, it has certain drawbacks, chiefly severe soft-tissue damage. Allium sativum (garlic extract) is a proven antimicrobial agent that has the ability to dissolve inorganic tissue with minimal toxicity. However, its ability to remove smear layer (SL) is not known. Conventional hand-held syringe irrigation is ineffective in removing canal debris. The use of newer irrigation systems is limited owing to their high cost. Modified evacuation system (MES) may prove to be an effective yet economical alternative.Aims:This study aims to evaluate the SL removing capacity of garlic extract as an alternative to 5% NaOCl and the use of modified evacuation system for removal of irrigant along with debris from root canals.Settings and Design:Sixty-eight single-rooted mandibular premolars were divided into 8 Groups: Two control Groups A and B (4 samples each) and six experimental Groups C to H (10 samples each). Garlic extract was prepared at a concentration of 64 mg/ml. MES was set up using 21-gauge flat-end needle fixed onto chair side high-volume evacuation system.Subjects and Methods:Control groups were irrigated with normal saline, Groups C and D with 5% NaOCl and 17% ethylenediaminetetraacetic acid (EDTA), Groups E and F with garlic extract and 17% EDTA and Groups G and H with plain garlic extract. MES was used in Groups B, D, F, and H. Scanning electron microscope analysis was done to view SL at coronal, middle, and apical thirds.Statistical Analysis Used:Chi-square test.Results:Groups A and B showed least scores. At coronal and middle thirds, Group D shows better results, followed by Groups F and H. Apically, Group F showed better results. Groups C and H, and E and G showed similar results. All groups with MES showed better results.Conclusions:A. sativum has an SL removal capacity. MES is effective in debris removal.

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Section: Discussionmentioning

confidence: 99%

“…Garlic ( Allium sativum ) has the capacity to remove the inorganic tissue and has good antibacterial capacity, with minimal side effects. [ 3 4 ] However, very few studies have been done on its ability to remove SL from root canals.…”

Section: Introductionmentioning

confidence: 99%

A scanning electron microscope evaluation of efficacy of sodium hypochlorite and Allium sativum in smear layer removal in root canals with the use of modified evacuation system: An ex vivo study

Prabhakaran

Mariswamy

2018

J Conserv Dent

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“…With the demand for new biocompatible and antimicrobial agents, nano scale material of silver nanoparticles (AgNPs) and allium sativum oil (garlic oil) may pay more attention in the coming years as alternative filling materials for pulpally involved and treated deciduous teeth. Both materials have a therapeutic effect via its broad spectrum antibacterial effect as well as its less cytotoxic effect without the development of drug resistance (8,9) .…”

Section: Introductionmentioning

confidence: 99%

Nanosilver Gel Versus Zinc Oxide-Allium Sativum Oil Paste as Obturation Materials following Partial Pulpectomy of Primary Molars: An in vivo study

2020

Al-Azhar Journal of Dental Science

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Objective: The aim of this study was to evaluate the clinical and radiographic success of nanosilver gel in paste form versus zinc oxide allium sativum oil paste as obturation materials following partial pulpectomy in primary molar. Subjects and methods: Forty eight primary molars of forty eight children aged between 4 and 8 years with pulpally involved primary molars requiring root canal procedures were equally divided to 3 groups and treated with nanosilver paste zinc oxide allium sativum oil paste and zinc oxide eugenol as obturation materials following partial pulpectomy procedure. The subjects were followed up clinically and radiographically at one week, 6 weeks and 3 months, respectively. Results: The results showed that the clinical and radiographic success rates of nanosilver gel in paste form and zinc oxide allium sativum oil paste over 3 months periods of observation were 100% whereas, for zinc oxide allium sativum oil and zinc oxide eugenol paste, the results were 87.5% and 81.25%, respectively. Conclusion: On the basis of the overall success rates of all the three obturation material, following order of performance can be inferred clinical and radiographic success :-nanosilver paste > zinc oxide allium sativum paste > zinc oxide eugenol paste.

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“…A . sativum has a therapeutic effect via its broad spectrum antibacterial effect as well as its less cytotoxic effect (Khan et al, ; Prabhakaran & Mariswamy, ). However, a number of studies have been performed to assess A .…”

Section: Introductionmentioning

confidence: 99%

Allium sativum extract as an irrigant in pulpectomy of primary molars: A 12‐month short‐term evaluation

Elheeny

2019

Clinical & Exp Dental Res

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This study indented to assess the clinical and radiographic assessment of Allium sativum extract as an intracanal irrigant for pulpectomy of primary molars. Ninety children with 110 teeth submitted were categorized into two groups. Clinical and radiographic success rates were checked at 3, 6, and 12 months. Qui‐square test at a level of significance was ˂0.05. There was no statistically significant difference ( p ˂ .05) between the two groups that has not been detected clinically or radiographically. Clinical and radiographic success rates of garlic extract at 3 months were (80% and 72.7%), which declined at 6 and 12 months to be 76.4% 6 and 74.5% respectively. For NaOCl group, clinical and radiographic success rates were 87.3% and 85.5% at 3 months, 87.3% and 87.3% at 6 months and 89.1% and 87.3% at 12 months. A . sativum extract can be used efficiently as an irrigant for pulpectomy of primary molar root canals.

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Anti-microbial efficacy of Allium sativum against Streptococcus mutans biofilm formation on orthodontic mini-implants

Cited by 12 publications

References 0 publications

A scanning electron microscope evaluation of efficacy of sodium hypochlorite and Allium sativum in smear layer removal in root canals with the use of modified evacuation system: An ex vivo study

A scanning electron microscope evaluation of efficacy of sodium hypochlorite and Allium sativum in smear layer removal in root canals with the use of modified evacuation system: An ex vivo study

Nanosilver Gel Versus Zinc Oxide-Allium Sativum Oil Paste as Obturation Materials following Partial Pulpectomy of Primary Molars: An in vivo study

Allium sativum extract as an irrigant in pulpectomy of primary molars: A 12‐month short‐term evaluation

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