Anti-mycobacterial, -oxidative, -proliferative and -inflammatory activities of dichloromethane leaf extracts of Gymnosporia senegalensis (Lam.) Loes

Makgatho, Marema Ephraim; Nxumalo, Winston; Raphoko, Lerato

doi:10.1016/j.sajb.2017.11.002

Cited by 19 publications

(8 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Antiobesity (Pierce, 1999;Preuss et al, 2004), antidiabetic (Sugihara et al, 2000, hypolipidaemic (Bishayee and Chatterjee, 1994), antimicrobial (Satdive and Abhilash, 2003), antiinflammatory (Malik et al, 2008), free radical scavenging activity (Ohmori et al, 2005) Gymnosporia senegalensis Diarrhea (de Wet et al, 2010), microbial diseases (Ngezahayo et al, 2015); South Africa: impotence (Semenya et al, 2013) Antibacterial (Mathabe et al, 2006), antibacterial andcytotoxic (Tatsimo et al, 2019), antimycobacterial (Makgatho et al, 2018) Holostylon robustum Tuberculosis, vertigo, cough (Bossard, 1996) -…”

Section: Species Previously Reported Ethnomedicinal Uses Reported Pharmacological Propertiesmentioning

confidence: 99%

Medicinal plants used by ‘root doctors’, local traditional healers in Bié province, Angola

Novotná

Polesny

Pinto-Basto

et al. 2020

Journal of Ethnopharmacology

View full text Add to dashboard Cite

This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.

show abstract

Section: Species Previously Reported Ethnomedicinal Uses Reported Pharmacological Propertiesmentioning

confidence: 99%

Medicinal plants used by ‘root doctors’, local traditional healers in Bié province, Angola

Novotná

Polesny

Pinto-Basto

et al. 2020

Journal of Ethnopharmacology

View full text Add to dashboard Cite

show abstract

“…is an important medical plant in Africa. It is used to treat respiratory ailments and inflammations (da Silva et al, 2011;Makgatho et al, 2018).…”

Section: Celastraceaementioning

confidence: 99%

Typification of Celastrus senegalensis and C. europaeus (Celastraceae, Celastroideae)

Ferrer‐Gallego¹,

Lumbreras²

2020

abm

View full text Add to dashboard Cite

The nomenclatural types of Celastrus senegalensis Lam., basionym of the current name Maytenus senegalensis (Lam.) Exell, and C. europaeus Boiss., basionym of M. senegalensis subsp. europaea (Boiss.) Rivas Martínez ex Güemes & M.B. Crespo (Celastraceae, Celastroideae), are discussed. A specimen preserved in the herbarium P, at the Museum national d’Histoire naturelle of Paris, is treated in this work as the neotype of M. senegalensis, and a specimen kept in the herbarium G, at the Conservatoire et Jardin botaniques of Genève, is designated as the lectotype of M. senegalensis subsp. europea.

show abstract

“…Exell. 6 Previous biological studies reported that extracts from various parts (stem, leaves, bark, and root) of G. senegalensis exhibited antiinflammatory, 5,7,8 antimicrobial, 5,8 antiplasmodial, 9 antioxidant, 8 and antiproliferative 8 activities. In addition, compounds of different classes, including alkaloids, terpenoids, sugars, lignans, and flavonoids, have been reported from M. senegalensis.…”

Section: Introductionmentioning

confidence: 99%

“…In our effort to investigate the potential of G. senegalensis as source of lead compounds, we fractionated the non-polar (rich in chlorophyll) and polar fractions of ethyl acetate leaf extract. We report herein the isolation, antimicrobial, and antioxidant activities of one new megastigmane derivative (1) and eight known compounds (2)(3)(4)(5)(6)(7)(8)(9).…”

Section: Introductionmentioning

confidence: 99%

A new megastigmane, known porphyrinic and galloylated bioactive derivatives from the leaves of Gymnosporia senegalensis

Tatsimo

Tamokou

Toume

et al. 2022

Journal of Chemical Research

View full text Add to dashboard Cite

Investigation of the non-polar (rich in chlorophyll) and polar fractions of the ethyl acetate extract of Gymnosporia senegalensis (Lam.) Loes. leaves led to the isolation of nine compounds, including one new megastigmane derivative, (3 R*,5 S*,6 R*,7 E,9ξ)-7-megastigmene-3,6,9-triol-3- O-β-D-(6′- O-galloyl)glucopyranoside (1), four known galloylated derivatives (2, 3, 8, 9), three known chlorophyll derivatives (4–6), and one known fatty acid (7). The structures of the isolates were determined by means of spectroscopic and spectrometric data, as well as by comparison with literature values. The extracts and isolated compounds were tested for their antibacterial, antifungal, and antioxidant activities. The isolates showed weak to high antimicrobial activities with phaeophytin A (4) being the most active one whereas phaeophorbide-a (5) and Chlorine e6 trimethyl ester (6) exhibited the highest antioxidant activities.

show abstract

Anti-mycobacterial, -oxidative, -proliferative and -inflammatory activities of dichloromethane leaf extracts of Gymnosporia senegalensis (Lam.) Loes

Cited by 19 publications

References 33 publications

Medicinal plants used by ‘root doctors’, local traditional healers in Bié province, Angola

Medicinal plants used by ‘root doctors’, local traditional healers in Bié province, Angola

Typification of Celastrus senegalensis and C. europaeus (Celastraceae, Celastroideae)

A new megastigmane, known porphyrinic and galloylated bioactive derivatives from the leaves of Gymnosporia senegalensis

Contact Info

Product

Resources

About