2018
DOI: 10.21608/mjcu.2018.56556
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Anti-Nucleosome Antibody as a Marker of Systemic Lupus Erythematosus Activity

Abstract: Background: Systemic Lupus Erythematosus (SLE) is a chronic multisystem autoimmune disease that is highly heterogeneous in its presentation. Effective SLE patient care relies on serological biomarkers. There is high interest in the identification of autoantibodies other than Antinuclear Antibodies (ANA) and anti-double stranded DNA (Anti-dsDNA). Aim: To evaluate the use of antinucleosome (Anti-NCS) antibody as a single marker to detect disease activity and renal involvement in SLE patients. Methods and Materia… Show more

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