Anti-obesity effect of a traditional Chinese dietary habit—blending lard with vegetable oil while cooking

Abstract

Obesity, which is associated with dietary habits, has become a global social problem and causes many metabolic diseases. In China, both percentages of adult obesity and overweight are far lower compared to western countries. It was designed to increase the two levels of daily intake in human, namely 3.8% and 6.5%, which are recommendatory intake (25 g/d) and Chinese citizens’ practical intake (41.4 g/d), respectively. The mice were respectively fed with feeds added with soybean oil, lard or the oil blended by both for 12 weeks. In the mice fed with diet containing 3.8% of the three oils or 6.5% blended oil, their body weight, body fat rate, cross-sectional area of adipocytes, adipogenesis and lipogenesis in adipose were decreased, whereas hydrolysis of triglyserides in adipose was increased. This study demonstrated that the oil mixture containing lard and soybean oil had a remarkable anti-obesity effect. It suggests that the traditional Chinese dietary habits using oils blended with lard and soybean oil, might be one of the factors of lower percentages of overweight and obesity in China, and that the increasing of dietary oil intake and the changing of its component resulted in the increasing of obesity rate in China over the past decades.

Differential effects of Chinese high-fat dietary habits on lipid metabolism: mechanisms and health implications

“…However, our results in this study conflict our previous research findings [22]. This may be due to differences in fat energy, as our previous study supplied 25% fat energy compared to 35% fat energy that was supplied in the present study.…”

“…High fat diet with soybean oil induced high body weight more than high fat diet with palm oil and lard, which are both rich in SFAs [21]. In our previous study, traditional Chinese dietary habits of blending lard with SBO were proven to have anti-obesity effects when stimulated average oil intake of urban and rural residents in China [22]. This study aimed to investigate the effects of different fat/oil mixtures on lipid metabolism in mice when stimulated with typical Chinese residents' high fat diet.…”

“…The method of western blotting analysis of liver used was like that used in a previous study [22]. This method used antibodies including sterol regulatory-element binding proteins (SREBP)-1c (Biosynthesis Biotechnology Co., Ltd., Beijing, China), fatty acid synthase (FAS) (Epitomics, Inc. USA), peroxisome proliferator-activated receptor alpha (PPARα) (Epitomics, Inc. USA), hormone-sensitive lipase (HSL) (Santa Cruz, Inc. USA) glyceraldehyde 3phosphate dehydrogenase (Proteintech, Inc. USA), and horseradish peroxidase-conjugated secondary antibodies (Proteintech, Inc. USA).…”

Lard-Blended Vegetable Oil Diet Alleviates Metabolic Syndrome in Mice

“…Our previous study (under 25% fat energy) found that a mixture of lard and soybean oil could reduce body fat accumulation compared to lard or soybean oil 20 , it was also proved in present study (under 30% fat energy), and can be extended to sun ower oil. However, under 35% fat energy, the function cannot be observed 21 .…”

A Lard and Soybean Oil Mixture Alleviates Low-Fat–High-Carbohydrate Diet-Induced Nonalcoholic Fatty Liver Disease in Mice

“…However, in recent years, numerous randomized, double-blind controlled trials, and meta-analysis studies have found that compared with unsaturated fatty acids, intake of SFAs shows no significant difference in cardiovascular disease and obesity risks [23,24]. Previously, we established that a lard and soybean oil mixture was found to be beneficial for lipids metabolism in medium-fat diets [25]. In the present study, we explored the effectiveness of a lard and soybean oil mixture (an LFHC diet) in alleviating NAFLD.…”