Anti-PF4 antibodies and their relationship with COVID infection

Yang, Chieh; Wang, Irene; Chitkara, Akshit; Swankutty, Jibin; Patel, Rushin; Kubba, Samir V

doi:10.1016/j.htct.2023.11.012

Hematology, Transfusion and Cell Therapy

2024

DOI: 10.1016/j.htct.2023.11.012

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Anti-PF4 antibodies and their relationship with COVID infection

Chieh Yang,

Irene Wang,

Akshit Chitkara

et al.

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2024

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Catastrophic Thrombosis: A Narrative Review

Franchini,

Focosi,

Pezzo

et al. 2024

Semin Thromb Hemost

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Catastrophic thrombosis is a severe condition characterized by a hypercoagulable tendency, leading to multiple thromboembolic events in different blood vessels, usually within a short timeframe. Several conditions have been associated with the development of catastrophic thrombosis, including the catastrophic antiphospholipid syndrome, thrombotic anti-platelet factor 4 immune disorders, thrombotic microangiopathies, cancers, the hyper-eosinophilic syndrome, pregnancy, infections, trauma, and drugs. Thrombotic storm represents a medical emergency whose management represents a serious challenge for physicians. Besides the prompt start of anticoagulation, a patient's prognosis depends on early recognition and possible treatment of the underlying condition. In this narrative review, we summarize the main characteristics of catastrophic thrombosis, analyzing the various conditions triggering such life-threatening complication. Finally, an algorithm with the diagnostic workup and the initial management of patients with catastrophic thrombosis is presented.

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Catastrophic Thrombosis: A Narrative Review

Franchini,

Focosi,

Pezzo

et al. 2024

Semin Thromb Hemost

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show abstract

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Anti-PF4 antibodies and their relationship with COVID infection

Cited by 1 publication

References 44 publications

Catastrophic Thrombosis: A Narrative Review

Catastrophic Thrombosis: A Narrative Review

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