Anti-shivering effect of intrathecal tramadol versus intravenous tramadol in patients Received spinal anesthesia for lower limb surgery. A randomized controlled clinical trial

Azeem, Eman Mohammed Abd El; Abdel-Ghaffar, Mohamed; Al-Touny, Shimaa A.

doi:10.1080/11101849.2023.2167300

Cited by 1 publication

(3 citation statements)

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“…There are only few studies done on patients undergoing urological surgeries. There is only one study comparing IT and IV tramadol 9 conducted in patients undergoing lower-limb surgeries. Our study was designed to assess the efficacy of IT and IV tramadol in preventing post-anesthesia shivering in patients undergoing URSL.…”

Section: Discussionmentioning

confidence: 99%

“…Abd El Azeem et al, 9 conducted a study comparing the antishivering effects of IT tramadol (IT group) and IV tramadol (IV group) in patients undergoing lower-limb surgeries under spinal anesthesia. The IT group received 20 mg of tramadol intrathecally, and the IV group received 0.25 mg/kg of tramadol intravenously.…”

Section: Discussionmentioning

confidence: 99%

“…It has a role in the thermoregulation process. 4,9 IT tramadol causes suppression of sensory and motor conduction in the spinal cord. 10 Previous studies compared IT tramadol in different doses, with a placebo or with other drugs, to test its anti-shivering effect.…”

Section: Antishivering Effect Of Intrathecal Versus Intravenous Trama...mentioning

confidence: 99%

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Antishivering effect of intrathecal versus intravenous tramadol in patients undergoing urethroscopic lithotripsy under spinal anesthesia

Manasa M,

Jyoti Petkar,

Dokku Kirtana

et al. 2024

Asian J Med Sci

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Background: Shivering is the most common complication seen in the perioperative period in patients undergoing urological surgeries under spinal anesthesia. Intravenous tramadol is used for the treatment of shivering. Aims and Objectives: In this study, we wanted to assess the prophylactic effect of tramadol, intrathecal (IT) versus intravenous with the control group, in decreasing the incidence of shivering. Materials and Methods: Fifty-four eligible patients posted for urethroscopic lithotripsy (URSL) were randomly allocated into three equal groups – Group C: Received 2.5 mL 0.5% bupivacaine heavy + 0.5 mL normal saline intrathecally and 5 mL of normal saline intravenously, Group V: Received 2.5 mL of 0.5% bupivacaine heavy+0.5 mL normal saline intrathecally and 25 mg tramadol in 5 mL of normal saline intravenously, and Group T: Received 2.5 mL of 0.5% bupivacaine heavy + 25 mg (0.5 mL) of tramadol intrathecally and 5 mL of normal saline intravenously. The incidence and severity of shivering were noted. Onset of sensory and motor block, duration of post-operative analgesia, core body temperature, and adverse effects such as nausea, vomiting, and hypotension were noted. Results: The incidence of intraoperative shivering was significantly lower in Group T versus C (P=0.014) but comparable among Group I versus C (P=0.502) and Group T versus I (P=0.06). The duration of analgesia was significantly higher in Group T compared to Groups I and C (P<0.001). The additional tramadol requirement was significantly lower in Group T versus I and in Group T versus C but comparable among Group I versus C. Conclusion: The addition of 25 mg tramadol to IT 0.5% bupivacaine heavy is effective in preventing intraoperative shivering in patients undergoing urological surgeries like URSL.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%