Anti-Streptococcus mutans property of a chitosan: Containing resin sealant

Rajabnia, Ramazan; Ghasempour, Maryam; Gharekhani, Samane; Gholamhoseinnia, Sepide; Soroorhomayoon, Sepide

doi:10.4103/2231-0762.175405

Cited by 16 publications

(8 citation statements)

References 30 publications

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“…Studies that used CFU counting to assess the antibacterial effects found a significant reduction in CFU counts with 5% ZnM [ 10 ], 2.5 and 5% SnM [ 10 ], 2.5 and 5% METAC [ 11 ], 5% DMAHDM [ 21 , 27 ], 2% TAT [ 12 ], 0.5 and 1% ZnO [ 28 ], 0.5 and 1% CaF 2 [ 28 ], 4% MAE-DB [ 30 ], 2, 2.5, 3, 4 and 5% chitosan [ 31 , 34 ], 0.25, 0.5 and 1% Se [ 13 ], Teethmate F-1 [ 34 ], Seal & Protect [ 34 ] and 1% DMAE-CB [ 35 ] sealants in comparison to the controls or other tested groups ( Table 4 ). There was a wide variation in the data reported among the included studies.…”

Section: Resultsmentioning

confidence: 99%

The Antibacterial Effects of Resin-Based Dental Sealants: A Systematic Review of In Vitro Studies

et al. 2021

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This review aimed to assess the antimicrobial effects of different antibacterial agents/compounds incorporated in resin-based dental sealants. Four databases (PubMed, MEDLINE, Web of Science and Scopus) were searched. From the 8052 records retrieved, 275 records were considered eligible for full-text screening. Nineteen studies met the inclusion criteria. Data extraction and quality assessment was performed by two independent reviewers. Six of the nineteen included studies were judged to have low risk of bias, and the rest had medium risk of bias. Compounds and particles such as zinc, tin, Selenium, chitosan, chlorhexidine, fluoride and methyl methacrylate were found to be effective in reducing the colony-forming unit counts, producing inhibition zones, reducing the optical density, reducing the metabolic activities, reducing the lactic acid and polysaccharide production and neutralizing the pH when they are added to the resin-based dental sealants. In addition, some studies showed that the antibacterial effect was not significantly different after 2 weeks, 2 months and 6 months aging in distilled water or phosphate-buffered saline. In conclusion, studies have confirmed the effectiveness of adding antibacterial agents/compounds to dental sealants. However, we should consider that these results are based on laboratory studies with a high degree of heterogeneity.

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Section: Resultsmentioning

confidence: 99%

The Antibacterial Effects of Resin-Based Dental Sealants: A Systematic Review of In Vitro Studies

et al. 2021

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“…The antibacterial activity of chitosan could be attributed to its cationic nature. Cationic materials are able to degrade the cell wall structure and cell membrane of bacteria, which in turn leads to the exposure of the cell membrane to osmotic shock and exudation of the cytoplasmic content, eventually followed by cell death [29]. In a study in this regard, Costa et al [30] observed that chitosan was largely effective against the adherence and biofilm formation of S. mutans, and its action was evident in the inhibition of the initial adherence and biofilm formation and disruption of the mature biofilms.…”

Section: Discussionmentioning

confidence: 99%

Antimicrobial Activity of Colloidal Selenium Nanoparticles in Chitosan Solution against Streptococcus mutans, Lactobacillus acidophilus, and Candida albicans

Darroudi

Rangrazi

Ghazvini

et al. 2021

Pesqui. Bras. Odontopediatria Clín. Integr.

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Objective: To investigate the antimicrobial activity of colloidal selenium nanoparticles in chitosan solution (Cts-Se-NPs) against Streptococcus mutans, Lactobacillus acidophilus, and Candida albicans. Material and Methods: Cts-Se-NPs solution was prepared using a simple chemical reduction method. The MIC and MBC against S. mutans, L. acidophilus, and C. albicans were determined using the broth dilution assay. Results: The Cts-Se-NPs had remarkable antimicrobial activity against S. mutans, L. acidophilus, and C. albicans. The MIC values of the Cts-Se-NPs were lowest for S. mutans (0.068 mg/ml) compared to L. acidophilus (0.137 mg/ml), and C. albicans (0.274 mg/ml). The MBC values of the Cts-Se-NPs against the microorganisms after one, two, six, and 24 hours indicated that the concentration of 0.274 mg/ml of Cts-Se-NPs completely killed S. mutans, L. acidophilus, and C. albicans after one, two, and six hours, respectively. At the concentration of 0.137 mg/ml, S. mutans and L. acidophilus were killed after six and 24 hours, respectively. Conclusion: These findings encourage the potential use of Cts-Se-NPs in dentistry, while further clinical research is required in this area.

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“…Chitosan is a cationic material, as it contains one primary amine group. This polysaccharide can adhere to the bacterial cell wall and degrade its structure, as well as the cell membrane of bacteria [ 19 , 20 ]. Nanosized chitosan also exhibits superior antimicrobial activities [ 20 ].…”

Section: Introductionmentioning

confidence: 99%

Incorporation of Chitosan Nanoparticles into a Cold-Cure Orthodontic Acrylic Resin: Effects on Mechanical Properties

2021

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Improvement of the antibacterial properties of acrylic resins, used in the construction of removable orthodontic appliances, is an important strategy to reduce the incidence of caries and oral diseases in orthodontic treatments. The addition of antimicrobial agents to acrylic resins is one of the effective methods to enhance the antimicrobial properties of these materials. However, one main concern is that modification of acrylic resin has negative effects on its mechanical properties. Recently, chitosan nanoparticles (NPs), as biocompatible and biodegradable polysaccharides with remarkable antimicrobial properties, have been used in different areas of dentistry and medicine. This study aimed to investigate the effects of adding chitosan NPs on the mechanical properties of a cold-cure orthodontic acrylic resin. The chitosan NPs were added to the acrylic resin in various weight percentages: 0% (control), 0.5%, 1%, 2%, and 4%. The flexural strength, compressive strength, Vickers microhardness, and impact strength measurements were performed for all five groups. The results showed that adding up to 1% (w/w) chitosan NPs to an acrylic resin had no significant negative effects on its flexural strength and compressive strength, while it decreased these parameters at weight percentages of 2% and 4% (w/w). The results also revealed that modification of acrylic resin with chitosan NPs up to 4% had no significant negative effects on the microhardness and impact strength of acrylic resin. In conclusion, the addition of chitosan NPs up to 1% (w/w) had no significant negative effects on the mechanical properties of cold-cure acrylic resin.

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Anti-Streptococcus mutans property of a chitosan: Containing resin sealant

Cited by 16 publications

References 30 publications

The Antibacterial Effects of Resin-Based Dental Sealants: A Systematic Review of In Vitro Studies

The Antibacterial Effects of Resin-Based Dental Sealants: A Systematic Review of In Vitro Studies

Antimicrobial Activity of Colloidal Selenium Nanoparticles in Chitosan Solution against Streptococcus mutans, Lactobacillus acidophilus, and Candida albicans

Incorporation of Chitosan Nanoparticles into a Cold-Cure Orthodontic Acrylic Resin: Effects on Mechanical Properties

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