Anti-tuberculosis drug resistance in Karonga District: pattern and trend, 1986-2001

Mycobacterium tuberculosisBeijing Genotype, Northern Malawi

“…Cultures are also performed on lymph node aspirates and other samples as appropriate. Treatment follows Malawi National TB Control Programme guidelines, and drug resistance has remained low, with initial isoniazid resistance ≈6% during this study ( 7 , 8 ).…”

Trends in tuberculosis and the influence of HIV infection in northern Malawi, 1988–2001

“…The estimated fall in TB incidence that would have occurred in the absence of HIV infection, and the stability of drug resistance levels over the period even with an increased case load [17,18], suggest that the control programme is working well here. The impact of HIV on TB is finely balanced.…”

DNA Fingerprint Changes in Tuberculosis: Reinfection, Evolution, or Laboratory Error?

“…Before 1997, thiacetazone was used instead of ethambutol. Since 2001, for individuals with smear-positive TB, streptomycin has been replaced by ethambutol and, for individuals with smear-negative TB, the 12-month therapy regimen was replaced by 2 months of isoniazid, rifampicin, and pyrazinamide, followed by 6 months of isoniazid and ethambutol [17,18]. Since 2001, individuals have been kept in the hospital only for the initial 2 weeks, and some were treated entirely as outpatients.…”