1996
DOI: 10.1016/0304-3835(96)04233-4
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Anti-tumor activity of the crude saponins obtained from asparagus

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Cited by 108 publications
(84 citation statements)
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“…showed positive growth inhibition to the HT-29 cell lines. Studies by 26 Shao et al, (1996) also reported that an alcoholic extract from shoots exhibited antitumor activities and 27 Singh et al, (1992) reported their fruit to be the source of bile-stimulating agent. Reports from World Intellectual Property Organization (2010) also indicated that methanol extracts from various seaweed species have demonstrated cytotoxic effect on human cancer cell lines including HeLa, MCF-7 and MDA-MB-231.…”
Section: Discussionmentioning
confidence: 99%
“…showed positive growth inhibition to the HT-29 cell lines. Studies by 26 Shao et al, (1996) also reported that an alcoholic extract from shoots exhibited antitumor activities and 27 Singh et al, (1992) reported their fruit to be the source of bile-stimulating agent. Reports from World Intellectual Property Organization (2010) also indicated that methanol extracts from various seaweed species have demonstrated cytotoxic effect on human cancer cell lines including HeLa, MCF-7 and MDA-MB-231.…”
Section: Discussionmentioning
confidence: 99%
“…The terpenoids encompasses other classes of bioactive principles in diverse collections of plants. Notable examples include: mono-and sesquiterpene volatile derivatives from Antirrhinum tortuosum [182], mono-and sesquiterpenes from Phlomis fruticosa [183], saponins and sapogenins from Asparagus aphyllus [184], sesquiterpene lactones from Palaeocyanus crassifolius [185] tetraterpene carotenoids from Arum italicum [186], triterpenoids from Olea europaea [187,188] and β-sitosterol; a triterpene-like compound from Acanthus mollis [189] that exhibits plasma cholesterol lowering properties.…”
Section: Terpenoidsmentioning
confidence: 99%
“…Nuestro país es el segundo mayor productor y exportador de Asparagus officinalis en el mundo (12) , poseyendo esta especie gran actividad biológica como antimutagénica (13) e hipolipemiante (14,15) en el jugo; es antioxidante (16,17) y antitumoral (18) en el tallo; y antifúngica (19) , hipoglicemiante (20,21) , inmunoprotectora (22) y hepatoprotectora (23) en las raíces; esto debido a la actividad de sus componentes bioactivos como glutatión (24) , flavonoides (16,25) , saponinas esteroideas (16,26) y polisacáridos (16,27) . La mayoría de las investigaciones previas con esta especie han utilizado extractos etanólicos, metanólicos e hidroalcohólicos; sin embargo, en nuestro medio, la forma tradicional de consumir el espárrago verde es consumir la parte del tallo previamente cocinada, razón por la cual utilizamos en nuestra investigación el extracto acuoso del tallo de Asparagus officinalis con el objetivo de evaluar efecto hepatoprotector en daño inducido por fármacos antituberculosos de primera línea.…”
Section: Introductionunclassified