Anti‐tumour necrosis factor α‐induced lupus erythematosus panniculitis

Durand, Alain; Goussot, J. F.; Thiolat, Denis; Taı̈eb, Alain; Marie, Jérôme; Sénéschal, Julien; Darrigade, Anne‐Sophie

doi:10.1111/jdv.14103

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Primarily-lobular Panniculitides Primarily-lobular Panniculi1

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“…It can also appears concomitantly with discoid lupus erythematosus or subacute cutaneous lupus erythematosus (on the overlying skin or elsewhere), as well as an isolated phenomenon [43]. The development of LEP after an injury to the area, such as HPV vaccination, preceding trauma and injection site of adalimumab -a human monoclonal antibody to tumor necrosis factor (TNF)-α -has been previously described [44][45][46][47].…”

Section: Primarily-lobular Panniculitides Primarily-lobular Panniculimentioning

confidence: 99%

Panniculitides of particular interest to the rheumatologist

Morita

Trés

García³

et al. 2019

Adv Rheumatol

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The panniculitides remain as one of the most challenging areas for clinicians, as they comprise a heterogeneous group of inflammatory diseases involving the subcutaneous fat with potentially-shared clinical and histopathological features. Clinically, most panniculitides present as red edematous nodules or plaques. Therefore, in addition to a detailed clinical history, a large scalpel biopsy of a recent-stage lesion with adequate representation of the subcutaneous tissue is essential to specific diagnosis and appropriate clinical management. Herein we review the panniculitides of particular interest to the rheumatologist.

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