Anti-Ulcer Effect of Fractions of &lt;I&gt;Hydrolea zeylanica&lt;/I&gt; on Pyloric Ligated Induced Ulcers in Rats

Borkar, Vijay S.; Kumaran, K. Senthil; KUMAR, KAPIL; Gangurde, Hemant H; Chordiya, Mayur A

doi:10.1166/jpsp.2015.1061

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“…Metal oxide nanomaterials of CuO, Fe 3 O 4 , TiO 2 , and ZnO have been scrutinized for their biological activities. Among all the metal oxides, ZnO is widely used in the elimination of heavy metals (toxic elements), such as sulfur and arsenic, from the polluted water owing to their large surface area by the volume ratio than the bulk materials (1)(2)(3)(4)(5). Biosynthesis or green of nanoparticles (NPs) is an alternative novel approach to the synthesis of NPs using plant extracts, algae, fungi, yeast, and bacteria (6,7).…”

Section: Introductionmentioning

confidence: 99%

Antibacterial Agent of Echinochloa esculenta-Mediated ZnO Nanoparticles on Urinary Infection-Causing Bacteria

Stella Bharathy,

Dayana Jeyaleela,

Rosaline Vimala

et al. 2024

J Rep Pharm Sci

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Background: Echinochloa esculenta is the Indian Barnyard millet which is a grass type of species. This study focused on the evaluation of the antibacterial activity of Echinochloa esculenta-mediated zinc oxide nanoparticles (ZnONPs) against urinary tract infection (UTI) microbes, such as Escherichia coli (E. coli), Enterobacter aerogenes, Pseudomonas aeruginosa, Staphylococcus aureus, and Proteus vulgaris. Methods: The millet Echinochloa esculenta-mediated ZnONPs are synthesized using a green method. Synthesized ZnONPs are characterized by ultraviolet (UV), Fourier transform-infrared resonance spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM), and energy dispersive X-ray analysis (EDX) to determine the functional groups, crystalline size, shape, and elemental composition of the synthesized NPs. Results: The UV and FTIR results of Echinochloa esculenta-mediated ZnONPs preliminarily confirmed the formation of ZnONPs. The XRD and SEM results also confirmed that the synthesized ZnONPs are well-crystalline in nature, and the average size was observed to be 23.38 nm with a spherical shape. Echinochloa esculenta-mediated ZnONPs contained 73.33% of zinc and 26.77% of oxygen, which was examined by EDX. Synthesized ZnONPs were tested against the five UTI pathogens, and they exhibited a greater zone of inhibitions than zinc acetate and plant extract. Especially against S. aureus, Echinochloa esculenta-mediated ZnONPs performed well with an inhibitory effect. Conclusions: Therefore, this study had the potential value of developing new eco-friendly, low-cost, and less toxic nanomaterials that can be used as a bio-control for diseases.

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Section: Introductionmentioning

confidence: 99%