Anti-urolithiatic, antibacterial, anti-inflammatory and analgesic effects of Erica arborea flowers and leaves hydromethanolic extracts: An ethnopharmacological study

Amari, Salima; Karbab, Ahlem; Charef, Noureddine; Arrar, Lekhmici; Mubarak, Mohammad S.

doi:10.1016/j.sjbs.2023.103785

Saudi Journal of Biological Sciences

2023

DOI: 10.1016/j.sjbs.2023.103785

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Anti-urolithiatic, antibacterial, anti-inflammatory and analgesic effects of Erica arborea flowers and leaves hydromethanolic extracts: An ethnopharmacological study

Salima Amari,

Ahlem Karbab,

Noureddine Charef

et al.

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2024

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Antioxidative and anti-inflammatory activities of Erica spiculifolia extracts and fractions

Pavlović,

Dobrić,

Stojanović

et al. 2024

Natural Product Research

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There is little data on the phytochemical/pharmacological properties of Erica spiculifolia Salisb. (syn. Bruckentalia spiculifolia (Salisb.) Rchb.). This study examines the antioxidative and anti-inflammatory activities of different extracts and fractions of E. spiculifolia in vitro on isolated rat peritoneal macrophages, in the carrageenan-induced rat paw oedema test, BSA test, and two complementary antioxidant assays. Ethanolic extracts of leaves, flowers, and aboveground parts, and petroleum ether, ether, ethyl acetate, and water fractionations of the ethanol extract of E. spiculifolia applied at doses of 50-200 mg/kg p.o. exhibited dose-dependent anti-inflammatory activity comparable with indomethacin. All tested samples, except for the petroleum ether fraction, exerted excellent in vitro antioxidant activity, and all of them exhibited significant and similar inhibition of BSA denaturation comparable with diclofenac. Ethanolic extract of the aboveground parts obtained by percolation, ethyl acetate and water fractions had the highest efficiency, attenuating inflammation by more than 50% in the lowest applied concentration alongside exceptional radical scavenging activity.

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Antioxidative and anti-inflammatory activities of Erica spiculifolia extracts and fractions

Pavlović,

Dobrić,

Stojanović

et al. 2024

Natural Product Research

View full text Add to dashboard Cite

show abstract

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Anti-urolithiatic, antibacterial, anti-inflammatory and analgesic effects of Erica arborea flowers and leaves hydromethanolic extracts: An ethnopharmacological study

Cited by 1 publication

References 50 publications

Antioxidative and anti-inflammatory activities of Erica spiculifolia extracts and fractions

Antioxidative and anti-inflammatory activities of Erica spiculifolia extracts and fractions

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