Antiarrhythmic drugs part 2: rhythm-control drugs

Abstract

Rhythm-control drugs are used to terminate arrhythmias, and/or prevent their recurrence. They are a heterogeneous group of medicines with a wide range of indications, mechanisms and pharmacological properties. In this second article of a three-part series, three commonly used rhythm-control drugs are evaluated: adenosine, amiodarone and flecainide. In addition to describing each drug and its uses, important practice points are identified with the aim of promoting safe prescribing and administration.