Antiasthmatic and antiallergic potential of methanolic extract of leaves of Ailanthus excelsa

Kumar, Dinesh; Bhat, Zulfiqar Ali; Singh, P. K.; Khatanglakar, V.; Bhujbal, Santosh S.

doi:10.1590/s0102-695x2011005000032

Cited by 14 publications

(5 citation statements)

References 10 publications

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“…Significant (*p<0.05, **p<0.01, ***p<0.001) antiasthmatic activity was seen after treatment with a methanolic extract of at varying doses. The ability of (AER) leaves to stop or slow the production of inflammatory mediators makes their methanolic extract's antiasthmatic and antiallergic effects even stronger 25 .…”

Section: Antihistaminic Activity: Kumar Et Al;mentioning

confidence: 99%

Untitled

2023

IJPSR

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The genus Ailanthus, which includes both evergreen and deciduous species, is native to both Asia and northern Australia. Traditional medicine relies heavily on this plant, and various components of the plant are utilized to treat a wide range of illnesses. Herbal and ayurvedic drugs have gained worldwide attention over the past decade for their potential health and financial benefits. There are now major worries about the quality, safety, and efficacy of herbs due to their regular and extensive use around the world. As a result, credible scientific data or evaluation is required before health claims made about herbs may be considered valid. The foundation for this tree's status as a plant of heaven includes the traditional assertions, phytochemical studies, pharmacological examination and some ayurvedic formulations. Therapeutic effects are found throughout the plant. The bark is employed in treating dysentery, earaches, skin diseases, rectum problems, fever related to tridosha and alleviating thirst. Furthermore, it is prescribed for patients suffering from bronchitis, asthma, bronchitis, dyspepsia, gout and rheumatism. In Ayurveda, it is recommended for those with a sour palate. Extracts from the bark of the stem were shown to have strong antibacterial and antifungal properties. Flavonoids, quassinoids, alkaloids, terpenoids, sterols and saponins have all been found in this plant. Ethnobotanical research shows that Ailanthus excelsa Roxb (AER) is full of different chemical compounds that may have a wide range of effects on living things. The traditional claims, as well as the pharmacognostical, phytochemical, pharmacological, and future potential of this plant are discussed in this review. Researchers are still looking for ways to use naturally occurring molecules to treat human diseases, according to new information. This information also points the way toward discovering more naturally occurring and new semisynthetic or synthetic compounds with similar effects.

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Section: Antihistaminic Activity: Kumar Et Al;mentioning

confidence: 99%

Untitled

2023

IJPSR

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“…The tree can be raised from both seeds and stumps. The leaves are rated as highly palatable and nutritious fodder for sheep and goats and an average tree yields about 500-700 kg of green leaves twice a year (Kumar et al 2011;Chopra et al 1958;Database, 2000).…”

Section: Botanical Distributionmentioning

confidence: 99%

Screening of phytoconstituents and antibacterial effects of leaf & stem of Ailanthus excelsa against E. Coli, S. Aureus, A. Niger & A. Flavus

Sharma¹,

Maurya²,

Hussain³

2022

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The research was aimed as screening of phytoconstituents and antibacterial effects of Leaf & Stem of Ailanthus excelsa against E. Coli, S. Aureus, A. Niger & A. Flavus. The plants were collected from Bareilly region, Uttar Pradesh and authentication was done by CIMAP, Lucknow. The collected plant material was dried in shade and ground in the grounder. The dried powdered drug material was extracted by 9 different solvents by cold maceration for 12 hrs at room temperature. Mayer’s, Hager’s tests, Fehling’s Wager’s and Molisch test were used for detection of alkaloids, glycosides, saponins, terpenoids etc. After the extraction was complete, it was tested against various species such as E. coli, S. aureus, S. niger and A. Flavus for its antimicrobial potential. The results indicate that methanolic extract showed highest level of phytoconstituents such as alkaloids, glucosides, saponins, terpenoids, flavonoids, and carbohydrates. Extract showed significant antibacterial potential against all the species tested with. In conclusion, this research suggests, that novel molecules should be identified and isolated responsible for specific pharmacological activity.

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“…Difference in total leukocyte count and total eosinophilia count before and 24 h after drug administration was calculated 9 .…”

Section: Effect Of Test Drug On Leukocytosis Eosinophiliamentioning

confidence: 99%