Antibacterial activities of gold nanoparticles synthesized by Citrus limonum fruit extract

Mahmood, Haroon; Hussain, Syed Babar; Nosheen, Asia; Mahmood, Tariq; Shafique, Muhammad; Haq, Noaman Ul; Haq, Anwar Ul

doi:10.30848/pjb2021-6(36)

Cited by 4 publications

(2 citation statements)

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“…Moreover, it is noteworthy for its relevance to phenolic and flavonoid compounds, as they also display a pronounced vibration at this specific wavenumber ( Prathna et al, 2011 ). The presence of a peak at 1316 cm −1 signifies the stretching vibrations of C-N within the aromatic amines ( Mahmood et al, 2021 ). The asymmetric stretching vibrations occurring at 1160 cm −1 are associated with the C–O–C bond ( Rabbani et al, 2019 ).…”

Section: Resultsmentioning

confidence: 99%

Antibacterial and antibiofilm activity of Abroma augusta stabilized silver (Ag) nanoparticles against drug-resistant clinical pathogens

Kumar,

Khan,

Husain

et al. 2023

Front. Mol. Biosci.

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Infectious diseases remain among the most pressing concerns for human health. This issue has grown even more complex with the emergence of multidrug-resistant (MDR) bacteria. To address bacterial infections, nanoparticles have emerged as a promising avenue, offering the potential to target bacteria at multiple levels and effectively eliminate them. In this study, silver nanoparticles (AA-AgNPs) were synthesized using the leaf extract of a medicinal plant, Abroma augusta. The synthesis method is straightforward, safe, cost-effective, and environment friendly, utilizing the leaf extract of this Ayurvedic herb. The UV-vis absorbance peak at 424 nm indicated the formation of AA-AgNPs, with the involvement of numerous functional groups in the synthesis and stabilization of the particles. AA-AgNPs exhibited robust antibacterial and antibiofilm activities against methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococci (VRE). The MIC values of AA-AgNPs ranged from 8 to 32 μg/mL. Electron microscopic examination of the interaction of AA-AgNPs with the test bacterial pathogens showed a deleterious impact on bacterial morphology, resulting from membrane rupture and leakage of intracellular components. AA-AgNPs also demonstrated a dose-dependent effect in curtailing biofilm formation below inhibitory doses. Overall, this study highlights the potential of AA-AgNPs in the successful inhibition of both the growth and biofilms of MRSA and VRE bacteria. Following studies on toxicity and dose optimization, such AgNPs could be developed into effective medical remedies against infections.

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Section: Resultsmentioning

confidence: 99%

Antibacterial and antibiofilm activity of Abroma augusta stabilized silver (Ag) nanoparticles against drug-resistant clinical pathogens

Kumar,

Khan,

Husain

et al. 2023

Front. Mol. Biosci.

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“…It commands a substantial weight percentage of 74.52%, signifying its preeminence among the sample's constituents. Consequently, the spotlight firmly rests on gold in the context of the green synthesized AuNPs, affirming its central role in this nanomaterial composition and properties [28].…”

Section: Surface Morphology and Elemental Composition Of Aunps Using ...mentioning

confidence: 95%

Green Synthesis of Gold Nanoparticles using Aqueous Extract of <i>Allium tuberosum</i> Leaves

Eugenio,

De Guzman,

Sanidad

et al. 2024

JBBBE

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Gold nanoparticles (AuNPs) have garnered significant interest in the field of biomaterials and biomedical engineering due to their wide-ranging applications, excellent biocompatibility, low toxicity, and customizable stability. This study focuses on synthesizing AuNPs through an environmentally friendly approach, specifically by utilizing the aqueous leaf extract of Allium tuberosum as both a reducing and capping agent. The synthesized AuNPs were characterized using UV-Vis Spectroscopy, revealing an absorption peak at 548 nm within the surface plasmon resonance (SPR) of AuNPs. Morphological analysis conducted via SEM showed a mixture of rod-shaped and spherical-shaped AuNPs, with dimensions of 41.0 nm (width) and 181.6 nm (length) confirmed through DLS measurements. EDX analysis confirmed the high abundance of gold in the synthesized AuNPs. Furthermore, a zeta potential value of -26.2 mV indicates that the AuNPs have decent stability. Phytochemical analyses and FT-IR results implicated that the Saponin present in the Allium tuberosum leaf extract played a crucial role in reducing metal ions and stabilizing the AuNPs. The potential of Allium tuberosum leaf extract for synthesizing diverse metal nanoparticles highlights its promise for biomaterials and biomedical engineering. The synthesized AuNPs show versatility for applications like targeted drug delivery, non-invasive imaging, and emerging biomedical uses.

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Antibacterial efficiency of carbon dots against Gram-positive and Gram-negative bacteria: A review

Varghese

Balachandran

2021

Journal of Environmental Chemical Engineering

101

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Antibacterial activities of gold nanoparticles synthesized by Citrus limonum fruit extract

Cited by 4 publications

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Antibacterial and antibiofilm activity of Abroma augusta stabilized silver (Ag) nanoparticles against drug-resistant clinical pathogens

Antibacterial and antibiofilm activity of Abroma augusta stabilized silver (Ag) nanoparticles against drug-resistant clinical pathogens

Green Synthesis of Gold Nanoparticles using Aqueous Extract of <i>Allium tuberosum</i> Leaves

Antibacterial efficiency of carbon dots against Gram-positive and Gram-negative bacteria: A review

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