Antibacterial Activities Test of Ethanol Extracts of Kundur Fruit (Benincasa hispida Thunb. Cogn) on Salmonella typhi Bacteria

Abstract

One of the natural ingredients that can be used as medicinal plants is kundur fruit (Benincasa hispida Thunb. Cogn). Kundur is one of the plants that contain compounds that are efficacious in medicine. The people of the Moronene tribe in Southeast Sulawesi used to consume kundur fruit in a shredded way to treat typhoid caused by bacterium Salmonella typhi (S. Typhi). The general objective of this study was to determine the bioactivity of the ethanol extract of kundur fruit (B. hispida) as an antibacterial S. typhi. Determination of antibacterial activity was carried out using the broth microdilution method. The results showed that the ethanol extract of kundur fruit had inhibitory activity on the growth of S. typhi bacteria with a minimum inhibitory concentration (MIC) of 800 μg / mL. This activity was compared with chloramphenicol with a MIC value of 8 μg / mL. In conclusion, the ethanol extract of kundur fruit has the potential as a source of antibacterial compounds against S. typhi.

Metabolit Profilling and Antibacterial Activity of Ethanol Extract of the Unripe Fruit Peel of Kayu Banana (Musa paradisiaca L. Var. Kayu)

“…The results obtained showed that the largest percentage of extract amendments in Kayu banana unripe fruit extract was 18.7 % and close to Kayu banana unripe fruit peel extract by 18.52 %. The difference in the percent yield obtained is influenced by the amount of organic solvent, the characteristics of the content of secondary metabolite compounds and the extraction method used [20]. Based on phytochemical screening carried out, the compounds contained in unripe fruit extracts and unripe fruit peel extracts of banana Kayu are alkaloids, flavonoids, saponins, tannins, triterpenoids, polyphenols and anthraquinones.…”

“…Storage of simplicia that has become a powder is carried out by putting the fine simplisia into a tightly closed container and tightly closed to avoid exposure to sunlight or insect ingress and giving silica gel to absorb moisture [29]. The difference in the percent yield obtained is influenced by the amount of organic solvent, the characteristics of the content of secondary metabolite compounds and the extraction method used [20]. The unripe fruit flesh extract of the Kayu banana contains alkaloid compounds, saponins, tannins, triterpenoids and polyphenols [34,35].…”

The Effect of Combined Administration of Sea Urchin Gonad and Aloe Vera Suspension on the Enhancement of Macrophage Phagocytosis Activity in Male White Rats Induced by Salmonella Typhimurium

“…Salmonella typhimurium resides in the gastrointestinal system (small digestive tract) of humans and animals. The ideal temperature for the development of Salmonella typhimurium is 37°C, and it thrives at a pH of 6-8 (Supiati, 2022).…”