Antibacterial activity and chemical characteristics of several Western Australian honeys compared to manuka honey and pasture honey

Roshan, Niloufar; Rippers, Thomas; Locher, Cornelia; Hammer, Katherine A.

doi:10.1007/s00203-016-1308-3

Cited by 46 publications

(49 citation statements)

References 18 publications

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“…Some researchers have suggested that the levels of H 2 O 2 in honey may differ between types of honey regardless of botanical and geographical origin 14 . A few studies have attempted to determine the concentration of H 2 O 2 in different honey samples and to evaluate its effect on the overall antibacterial activity 15 , 27 – 30 . Many studies have shown a greater correlation between antibacterial activity against S. aureus and the amount of H 2 O 2 in honey samples.…”

Section: Discussionmentioning

confidence: 99%

Phytochemicals-mediated production of hydrogen peroxide is crucial for high antibacterial activity of honeydew honey

Bucekova

Buriova

Pekárik

et al. 2018

Sci Rep

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Honeydew honey is increasingly valued due to its pronounced antibacterial potential; however, the underlying mechanism and compounds responsible for the strong antibacterial activity of honeydew honey are still unknown. The aim of this study was to investigate the inhibition of bacterial growth of 23 honeydew honey samples. Activity of bee-derived glucose oxidase (GOX) enzyme, the content of defensin-1 (Def-1) and hydrogen peroxide (H2O2), and total polyphenol content were determined in the 23 honey samples. Our results demonstrated that antibacterial activity of honeydew honey was equivalent to medical-grade manuka and kanuka honey and was abolished by catalase. Although H2O2 is an important factor in the inhibition of bacterial growth, polyphenolic compounds and their interaction with H2O2 are the key factors responsible for high antibacterial activity of honeydew honey. In addition, our results indicated that the antibacterial activity of honeydew honey is not dependent on GOX-mediated production of H2O2 or the presence of Def-1.

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Section: Discussionmentioning

confidence: 99%

Phytochemicals-mediated production of hydrogen peroxide is crucial for high antibacterial activity of honeydew honey

Bucekova

Buriova

Pekárik

et al. 2018

Sci Rep

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“…The literature demonstrates the use of different dressings in venous leg ulcers [21][22][23][24][25][26][27]. The standard for many years was the bandage even if, recently, new studies have identified innovative strategies for the treatment of venous leg ulcers [73][74][75]. The authors of a recent systematic review of the literature (53) point out that the bandage even in the prevention and treatment of venous leg ulcers is hardly popular with patients.…”

Section: Discussionmentioning

confidence: 99%

Complementary Medicine and Venous Ulcers: Review of Literature

Se¹

2017

Health Care Current Reviews

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Introduction: Complementary medicine has ancient historical roots and its use is constantly changing. It alongside scientific medicine is useful in the treatment of many diseases, including oncological, respiratory, and dermatological. It is used in the treatment of pain and in the local treatment of various ulcers (lesions) skin. In particular, scientific medicine uses several treatments for venous ulcers with not completely effective outcomes. Effective treatment prevents complications and improves the quality of life of patients. There is scientific evidence on the efficacy of complementary medicine in the treatment of venous ulcers of the lower limbs. Methods:It was performed as a literature review on the databases: MEDLINE, EMBASE and COCHRANE with the aim of detecting the evidence of efficacy of complementary medicine interventions in the treatment of venous ulcers and ways to treat it. We used the keywords and thesaurus descriptors for complementary medicine. We included the following drawings of relevant studies to the subject of the research: systematic reviews randomized controlled trials (RCTs), case control studies, observational studies, case reports, studies, and expert opinion in English, conducted on humans. For the purpose of this research, 174 documents were identified, of which only 15 were relevant and were within the inclusion criteria.Results: An analysis of the literature shows that many studies have evaluated the effectiveness of aloe, calendula, standardized extract from the aerial parts of A. pichinchensis, Mimosa tenuiflora, modified linen bandages, products made of honey found on the market, herbal therapies, polarized light therapy combined with herbal and plant biomembranes. However, these findings are insufficient to support or deny that one treatment is more effective than another. These results are not widely generalizable because of the low number of samples studied. Conclusion:Despite the interest in complementary medicine and the treatment of venous ulcers, there is currently no truly effective treatment strategy. The detected evidence is insufficient to make significant changes in the treatment of venous leg ulcers with complementary medicine interventions. The available studies on the treatment of venous leg ulcers with products based on plants have not established the existence of a treatment that may be effective individually. Additional studies would be needed to demonstrate the efficacy of these treatments.

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“…The antibacterial activity of honey is related to several factors acting alone or in synergy. The most prominent of them are hydrogen peroxide, phenolic compounds, the pH of honey and the osmotic pressure exerted by honey 32,33 . Hydrogen peroxide is the major inhibitor substance of honey.…”

Section: Antibacterial Activitymentioning

confidence: 99%

“…Hydrogen peroxide is the major inhibitor substance of honey. Concentration values of this compound in different honeys result in their varying antimicrobial effects 33,34 .…”

Section: Antibacterial Activitymentioning

confidence: 99%

Functional properties of a new spread based on olive oil and honeybees

Tekiki¹,

Helal²,

Hassouna³

et al. 2018

Mediterr.J.Chem.,

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A new alimentary concept has been developed since the 80’s. This one is called “functional food”. In this context, the olive oil and honey are traditionally used in their initial state as a basic food. They are considered as a potential source of new bioactive products from which we can formulate several functional foods. This work will focus on the elaboration of a new spread of honey and olive oil using beeswax as an emulsifier. Physicalchemical characterization, antioxidant and antibacterial activity were evaluated. As for the phenols content, spreads prepared from thyme honey has the highest content (337 mg GAE/kg) compared to other spreads. The antioxidant activity was evaluated by three different methods namely: DPPH test, ABTS + test and the iron reduction method (FRAP) which proves that this last has a higher activity than the other spreads (EC50 of 70 mg /L using DPPH, EC50 of 20 mg /L using ABTS). An agar-well diffusion assay was used to assess the activity of honeys against seven bacteria strains. All prepared spreads honey samples showed highest antibacterial activity against all bacterial strains tested (diameter of ZI > 20mm). Hence, we note that our new spread proved by excellence to be a functional food due to the high content of phenols and the important antibacterial and antioxidant activities.

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Antibacterial activity and chemical characteristics of several Western Australian honeys compared to manuka honey and pasture honey

Cited by 46 publications

References 18 publications

Phytochemicals-mediated production of hydrogen peroxide is crucial for high antibacterial activity of honeydew honey

Phytochemicals-mediated production of hydrogen peroxide is crucial for high antibacterial activity of honeydew honey

Complementary Medicine and Venous Ulcers: Review of Literature

Functional properties of a new spread based on olive oil and honeybees

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