Antibacterial activity of beroline

Potapova, E. Yu.; Хайдаров, К. Х.; Sadykov, Yu. D.

doi:10.1007/bf00773616

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Ch30~ Ch30~1

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1997

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“…9-Berberoline chloride was obtained by thermal O'demethylation of berberine chloride according to [17]. The product had a melting temperature of 243 -247~ (with decomp.)…”

Section: Ch30~ Ch30~mentioning

confidence: 99%

Study of by-products obtained during sanguiritrine production fromMacleaya microcapra

1997

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Sanguiritrine is a plant antimicrobial preparation possessing a broad spectrum of action [1,2]. The active substance is obtained from the above-ground part of Macleaya microcapra (Maxim Fedde) and Macleaya cordata (Will& R. Br.) [3,4] Study of the raw plant materials of M. microcapra of various origin and quality showed that the extraction of technical-purity sanguiritrine is accompanied by the coprecipitation of by-products responsible for the deeper coloration of the target technical products. Thin-layer chromatograms on a silica gel exhibited an additional spot having an orange-red color and a lower mobility compared to those of sanguinarine and chelerythrine.The impurity compound was extracted from the aqueous phase in the form of bisulfate. UV spectrum [Lm~, nm (log s)

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“…9-Berberoline chloride was obtained by thermal O'demethylation of berberine chloride according to [17]. The product had a melting temperature of 243 -247~ (with decomp.)…”

Section: Ch30~ Ch30~mentioning

confidence: 99%