Antibacterial activity of black myrobalan (Terminalia chebula Retz) against Helicobacter pylori

The development of Terminalia chebula Retz. (Combretaceae) in clinical research

“…chebula exhibited antibacterial activity against a number of both Gram-positive and Gram-negative human pathogenic bacteria [47][48][49] . Ethanedioic acid and ellagic acid isolated from butanol fraction of T. chebula fruit extract had strong antibacterial activity against intestinal bacteria, Clostridium perfingens and Escherichia coli [50] .…”

“…Ethanedioic acid and ellagic acid isolated from butanol fraction of T. chebula fruit extract had strong antibacterial activity against intestinal bacteria, Clostridium perfingens and Escherichia coli [50] . It is effective in inhibiting the urease activity of Helicobactor pyroli, Cytoprotective, anti-arthritic activity 41,75 an ubiquitous bacterium implicated in the development of gastritis, ulcers and stomach cancers [49] . GA and its ethyl ester isolated from ethanolic extract of T. chebula showed antimicrobial activity against methicillin-resistant Staphylococcus aureus(S. aureus) [51] .…”

Phytopharmacological overview of Terminalia chebula Retz

“…15 It is effective against Helicobactor pyroli by inhibiting the urease activity, and ubiquitous bacterium which cause stomach cancer, ulcers and gastritis. 14 The methicillin resistant Staphylococcus aureus when treated with the extract of T. chebula showed decreased growth and activity thereby confirming the anti bacterial activity. The ripe seeds of T. chebula also have strong anti bacterial activity against S. aureus.…”

“…chebula showed anti bacterial activity against both Gram positive and Gram negative human pathogenic bacteria. 13,14 Ethanedioic acid and ellagic acid isolated from T. Chebula fruit extract had strong anti bacterial activity against intestinal bacteria, Clostridium perfingens and Escherichia coli. 15 It is effective against Helicobactor pyroli by inhibiting the urease activity, and ubiquitous bacterium which cause stomach cancer, ulcers and gastritis.…”

Study of antibacterial activity of selected Iranian plant extracts on Helicobacter pylori

“…The results showed that these compounds (particularly monomeric tannin) have significant anti H. pylori activities due to their impact on lipid bilayer membranes [39]. Ehasnifar examined anti H. pylori effects of several plants, including pennyroyal and flowering oregano, and found that pennyroyal had no significant effect of growth inhibition while oregano significantly inhibited H. pylori growth [40]. Our findings indicated the highest level of anti H. pylori activity in aqueous extract of G. glabra followed by extracts of F. ulmaria, R. fruticosus, A. anserine and C. douglasii.…”