Antibacterial activity of Blumea balsamifera leaf extracts from Aceh, Indonesia

Abstract

Abstract. Masyudi, Noviyanti A, Ridhwan M, Nurman S, Jailani, Armi, Rafsanjani TM, Usman S, Hanafiah M, Marlina. 2023. Antibacterial activity of Blumea balsamifera leaf extracts from Aceh, Indonesia. Biodiversitas 24: 4584-4589. Blumea balsamifera L. has long been used as traditional medicine by communities in Aceh, Indonesia and from various parts of the world. For generations, this plant has been believed to have properties to cure various diseases. The results of the GCMS analysis of B. balsamifera leaf from Aceh-Indonesia in the previous study contain various compounds for wound healing, including borneol, jasmoline, camphor, and caryophyllene. The present study aimed to analyze the antibacterial activity of B. balsamifera leaves from Aceh. The sample was taken from the village of Gunongpulo, South Aceh-Indonesia, and the extraction process was carried out using three different types of solvents: ethanol, ethyl acetate, and n-hexane. Three variations of the extract obtained were then tested for antibacterial against Staphylococcus aureus and Pseudomonas aeruginosa by analyzing the inhibitory of each extract. The results showed that the inhibition zone formed on S. aureus against ethanol extract was 2.4 mm, ethyl extract was 9.2 mm, and n-hexane extract was 2.3 mm. In comparison, the inhibition zone formed on P. aeruginosa against ethanol extract was 0 mm, ethyl extract was 9 mm, and n-hexane extract was 4.9 mm. Conclusion: B. balsamifera leaf extract from Aceh contains antibacterial, with the highest inhibition against S. aureus at 9.2 mm and Pseudomonas at 9.0 mm. It is recommended that in the process of extracting B. balsamifera leaves by maceration, the best solvent used is ethyl acetate.

Antibacterial activity of faloak (Sterculia quadrifida) leaves extract

“…2017) observed that ethyl acetate was the most active fraction in inhibiting the bacteria compared to the n-hexane and methanol fractions. Masyudi et al (2023) also reported that ethyl acetate extract of Blumea balsamifera leaves showed the largest inhibitory zone diameter compared to ethanol and hexane extract of Blumea balsamifera leaves could inhibit the growth of Staphylococcus aureus and Pseudomonas aeruginosa. The ethyl acetate fraction attracts semi polar compounds in S. quadrifida leaves extract, which can inhibit bacterial growth.…”