2002
DOI: 10.1016/s0168-1605(01)00717-6
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Antibacterial activity of chitosans and chitosan oligomers with different molecular weights

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Cited by 1,366 publications
(753 citation statements)
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References 22 publications
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“…Likewise, Chaiyakosa et al (2007) obtained reductions of 81 and 96% while applying 0.25% chitosan solutions for 10 and 30 min, respectively, on shrimp infected with V. parahaemolyticus. Lower values were reported by No et al (2002), who used 0.1% chitosan against V. parahaemolyticus and obtained a 50% reduction. In another study, Terzi & Gucukoglu (2010) tested 0.05% chitosan for 30 min against V. parahaemolyticus and obtained a 33% reduction in mussels.…”
Section: Microbiological Analysesmentioning
confidence: 63%
“…Likewise, Chaiyakosa et al (2007) obtained reductions of 81 and 96% while applying 0.25% chitosan solutions for 10 and 30 min, respectively, on shrimp infected with V. parahaemolyticus. Lower values were reported by No et al (2002), who used 0.1% chitosan against V. parahaemolyticus and obtained a 50% reduction. In another study, Terzi & Gucukoglu (2010) tested 0.05% chitosan for 30 min against V. parahaemolyticus and obtained a 33% reduction in mussels.…”
Section: Microbiological Analysesmentioning
confidence: 63%
“…The antimicrobial activity of chitosan is dependent on its molecular weight and degree of deacetylation. 29 Fujiwara et al 15 have proved that the highly deacetylated and lower molecular chitosan showed bactericidal activity. Present findings suggested that the supplementation of chitosan to dentifrice is an effective method to control the demineralization of enamel around brackets.…”
Section: Discussionmentioning
confidence: 99%
“…Proses penghambatan pertumbuhan mikroba berkaitan dengan karakteristik chitosan sebagai agen antimikroba (Rabea et al, 2003). Kemampuan chitosan sebagai agen antimikroba juga berkaitan dengan kemampuannya melapisi bahan, mengikat air daging dan memiliki gugus amino yang reaktif serta berfungsi sebagai chelating agent yang secara selektif mengikat mineral misalnya zat besi sehingga menghambat pertumbuhan dan mencegah produksi toksin oleh mikroba (No et al, 2002 Mekanisme utama chitosan dalam menghambat pertumbuhan mikroba adalah chitosan mempunyai gugus amino positif yang mampu mengikat gugus karboksilat negatif yang berada dipermukaan sel bakteri (Rabea et al, 2003 ). Beberapa ikatan elektrokimia dapat mengubah distribusi muatan positif dan negatif pada permukaan membran sel, sehingga menyebabkan pelemahan atau kerusakan membran diikuti komponen sel mikroba (Juneja et al, 2006).…”
Section: Hasil Dan Pembahasanunclassified