Antibacterial Activity of Copper Nanoparticles-Chitosan Composite against <i>Vibrio parahaemolyticus</i>

Abstract

The Mekong Delta, Vietnam has traditionally been the major region of aqua produce accounting for over 52% of national aqua crop, and 65% of aqua export. In 2018, the aqua export value was over US$ 8.8 billion dollars, to which export of shrimp contributed 45%. However, pathogen infections directly influence the production and value-added contribution of shrimp in the region. The most common and serious infection is Early Mortality Syndrome (EMS) (or Acute Hepatopancreatic Necrosis Syndrome -AHPNS) caused by Vibrio parahaemolyticus. It has caused a severe economic loss for shrimp industry in various countries such as Vietnam (Oanh et al., 2013) , Malaysia (Kua et al., 2016) , Thailand (Joshi et al., 2014 , etc.Copper nanoparticles (CuNPs) have attracted attention of researchers in recent years owing to their low-cost, abundance and remarkable antimicrobial activity. Previous studies have reported antimicrobial properties of CuNPs against Micrococcus luteus,

Potentialities of bioinspired metal and metal oxide nanoparticles in biomedical sciences

“… 213 Similarly, chitosan-based copper nanoparticles exhibited efficient antibacterial activity against Vibrio parahaemolyticus . 214 Furthermore, biogenic metal and metal oxide nanoparticles exhibited antibacterial efficiency by various methods like damaging the plasma membrane (which leads to the bursting of the bacterial cells), the generation of excess ROS in the bacterial cell (which will lead to the increase in oxidative stress inside the cell), or the slow release of the drug (which will target the organelle), as described in Fig. 7 .…”