Antibacterial activity of date palm cake extracts (<i>Phoenix dactylifera</i>)

ALrajhi, Maha; AL-Rasheedi, Mabrouk; Eltom, Salah Elnaeem M.; Alhazmi, Yasir; Mustafa, Mustafa Mohammed; Ali, Alreshidi Mateq

doi:10.1080/23311932.2019.1625479

Cited by 33 publications

(17 citation statements)

References 16 publications

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“…DPF is well-known for its antimicrobial activities because it possesses antibacterial, antifungal, and antiviral properties. Several parts of the date palm tree can be used for medicinal purposes such as the dried leaves [ 25 , 64 ], fruit [ 64 – 66 ], pollen [ 67 , 68 ], seed [ 64 , 68 , 69 ], and tree bark extracts [ 64 ]. A date palm fruit consists of several components such as skin (epicarp), pulp (mesocarp), endocarp, and seed (kernel or pit) [ 15 ].…”

Section: Antimicrobial Activitymentioning

confidence: 99%

Bioactivity and Pharmacological Potential of Date Palm (Phoenix dactylifera L.) Against Pandemic COVID-19: a Comprehensive Review

Zain

Kari

Dawood

et al. 2022

Appl Biochem Biotechnol

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A novel coronavirus disease (COVID-19) or severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2), transmitted from person to person, has quickly emerged as the pandemic responsible for the current global health crisis. This infection has been declared a global pandemic, resulting in a concerning number of deaths as well as complications post-infection, primarily among vulnerable groups particularly older people and those with multiple comorbidities. In this article, we review the most recent research on the role of date palm ( Phoenix dactylifera L.) fruits (DPFs) to prevent or treat COVID-19 infection. The mechanisms underlying this preventive or therapeutic effect are also discussed in terms of bioactivity potentials in date palm, e.g., antimicrobial, antioxidant, anticancer, anti-diabetic, anti-inflammatory, neuroprotective, and hemolytic potential, as well as prospect against COVID-19 disease and the potential product development. Therefore, it can be concluded that regular consumption of DPFs may be associated with a lower risk of some chronic diseases. Indeed, DPFs have been widely used in folk medicine since ancient times to treat a variety of health conditions, demonstrating the importance of DPFs as a nutraceutical and source of functional nourishment. This comprehensive review aims to summarize the majority of the research on DPFs in terms of nutrient content and biologically active components such as phenolic compounds, with an emphasis on their roles in improving overall health as well as the potential product development to ensure consumers’ satisfaction in a current pandemic situation. In conclusion, DPFs can be given to COVID-19 patients as a safe and effective add-on medication or supplement in addition to routine treatments.

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Section: Antimicrobial Activitymentioning

confidence: 99%

Bioactivity and Pharmacological Potential of Date Palm (Phoenix dactylifera L.) Against Pandemic COVID-19: a Comprehensive Review

Zain

Kari

Dawood

et al. 2022

Appl Biochem Biotechnol

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“…e ethanol extract from the fruits was the most active against Gram-positive and Gram-negative bacteria and showed the highest antifungal action against C. albicans (MIC value of 0.15 mg/ml). ree types of dates from Oman (Mabseeli, Um-sellah, and Shahal) have also been described to possess strong antimicrobial activities [108]. e antimicrobial activities of date seeds are due to the occurrence of high amounts of phenolic compounds, such as p-coumaric, ferulic and sinapic acids, flavonoids, and procyanidins [109].…”

Section: Cyprusmentioning

confidence: 99%

Phytomedicine from Middle Eastern Countries: An Alternative Remedy to Modern Medicine against Candida spp Infection

Alam

Khan

2021

Evidence-Based Complementary and Alternative Medicine

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Candida spp are capable of infecting both normal and immunocompromised individuals. More recently, Candida infections have spread considerably in healthcare settings, especially in intensive care units, where it is the most frequently encountered pathogen. Candida albicans is the commonest species encountered, although infections by non-albicans species have also risen in the past few years. The pathogenicity of Candida is credited to its aptitude to change between yeast and hyphal modes of growth. Candida spp produce biofilms on synthetic materials that protect them and facilitate drug resistance and act as a source for chronic and recurrent infections. Primarily, azoles antifungal agents are utilized to treat Candida infection that targets the ergosterol synthesis pathway in the cell wall. The development of antifungal resistance in Candida species is a major reason for treatment failure, and hence, there is a need to develop newer antifungal molecules and/or modifications of existing antifungals to make them more effective and less toxic. This has led researchers to oversee the plants to discover newer antimicrobials. Middle Eastern countries are well known for their landscape ranging from dry and sandy deserts to snow-capped mountains. However, they comprise enormous plant diversity with over 20,000 different species showing various types of bioactivities, such as anticancer, antidiabetic, and antimicrobial activities. Especially, the antifungal potential of these phytoproducts could be exploited in the clinical setting for therapy. The present review examines some of the promising alternative natural compounds that have been tested and found effective in treating Candida infections in vitro in some Middle Eastern countries.

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“…The antimicrobial activities of date seeds are due to the presence of phenolic compounds, such as p-coumaric, ferulic and sinapic acids, flavonoids, and procyanidins [50]. Three types of dates from Oman (Mabseeli, Um-sellah, and Shahal) have also been reported to have high phenolic content, rich in antioxidant and strong antimicrobial activity [82].…”

Section: Antimicrobial Activitymentioning

confidence: 99%

Middle Eastern Plant Extracts: An Alternative to Modern Medicine Problems

et al. 2020

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Middle Eastern countries are primarily known for their dry sand deserts; however, they have a wider physiographic range which includes upland plateau and mountain ranges. The Middle East is home to various types of plants, such as Phoenix dactylifera (date palm tree), Scrophularia striata (herbaceous plants), and Opuntia ficus-indica (cactus). These plants have been found to have various types of bioactivities, such as antimicrobial activities against both bacteria and fungi, in addition to exhibiting anti-inflammatory effects and anti-cancer characteristics which can be utilized in the clinical setting for treatment. Due to limited reviews focusing on plant extracts from the Middle East, we aim to provide a discourse on plants from this region which have various bioactivities and to provide information on the compounds that can be identified from these plants. This is to enhance our understanding to improve modern medicine problems such as antimicrobial resistance and to find an alternative cure for cancer. It is hoped that the collation of information from this review will enable an assessment of the direct role of Middle Eastern plants in providing therapeutic options to address the predicaments in the medical field.

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Antibacterial activity of date palm cake extracts (Phoenix dactylifera)

Cited by 33 publications

References 16 publications

Bioactivity and Pharmacological Potential of Date Palm (Phoenix dactylifera L.) Against Pandemic COVID-19: a Comprehensive Review

Bioactivity and Pharmacological Potential of Date Palm (Phoenix dactylifera L.) Against Pandemic COVID-19: a Comprehensive Review

Phytomedicine from Middle Eastern Countries: An Alternative Remedy to Modern Medicine against Candida spp Infection

Middle Eastern Plant Extracts: An Alternative to Modern Medicine Problems

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